Organoids of the male reproductive system: Challenges, opportunities, and their potential use in fertility research

D Patrício, J Santiago, JF Mano… - WIREs Mechanisms of …, 2023 - Wiley Online Library
Organoids are units of function of a given organ able to reproduce, in culture, a biological
structure similar in architecture and function to its counterpart in vivo. Today, it is possible to …

Tuneable hybrid hydrogels via complementary self-assembly of a bioactive peptide with a robust polysaccharide

K Firipis, M Boyd-Moss, B Long… - ACS Biomaterials …, 2021 - ACS Publications
Synthetic materials designed for improved biomimicry of the extracellular matrix must
contain fibrous, bioactive, and mechanical cues. Self-assembly of low molecular weight …

Surface-templated glycopolymer nanopatterns transferred to hydrogels for designed multivalent carbohydrate–lectin interactions across length scales

A Singh, JC Arango, A Shi, JB d'Aliberti… - Journal of the …, 2023 - ACS Publications
Multivalent interactions between carbohydrates and proteins enable a broad range of
selective chemical processes of critical biological importance. Such interactions can extend …

Adjusting degree of modification and composition of gelAGE-based hydrogels improves long-term survival and function of primary human fibroblasts and endothelial …

H Genç, A Cianciosi, R Lohse, P Stahlhut… - …, 2023 - ACS Publications
This study aimed to develop a suitable hydrogel-based 3D platform to support long-term
culture of primary endothelial cells (ECs) and fibroblasts. Two hydrogel systems based on …

Exploring the properties and potential of the neural extracellular matrix for next‐generation regenerative therapies

JA Ortega, GP Soares de Aguiar… - Wiley …, 2024 - Wiley Online Library
The extracellular matrix (ECM) is a dynamic and complex network of proteins and molecules
that surrounds cells and tissues in the nervous system and orchestrates a myriad of …

Advances in biomimetic hydrogels for organoid culture

L Luo, L Liu, Y Ding, Y Dong, M Ma - Chemical Communications, 2023 - pubs.rsc.org
Organoid is a 3-dimensional (3D) cell culture system that mimics the structural and
functional characteristics of organs, and it has promising applications in regenerative …

Thiol-ene “click reactions” as a promising approach to polymer materials

DS Kazybayeva, GS Irmukhametova… - … Science, Series B, 2022 - Springer
This review is devoted to relatively new and promising approach to the synthesis of novel
organic compounds and polymer materials, based on the “click chemistry” concept. Several …

The interplay between extracellular matrix and progenitor/stem cells during wound healing: Opportunities and future directions

M Rasouli, A Rahimi, M Soleimani - Acta Histochemica, 2021 - Elsevier
Skin wound healing, a dynamic physiological process, progresses through coordinated
overlapping phases to restore skin integrity. In some pathological conditions such as …

Characterization of a bioink combining extracellular matrix-like hydrogel with osteosarcoma cells: preliminary results

G Loi, G Stucchi, F Scocozza, L Cansolino… - Gels, 2023 - mdpi.com
Three-dimensional (3D) bioprinting allows the production of artificial 3D cellular
microenvironments thanks to the controlled spatial deposition of bioinks. Proper bioink …

Injectable hydrogels in stroke and spinal cord injury treatment: a review on hydrogel materials, cell–matrix interactions and glial involvement

PH Lin, Q Dong, SY Chew - Materials Advances, 2021 - pubs.rsc.org
Central nervous system (CNS) pathologies, such as stroke and spinal cord injury, remain
debilitating issues due to the inhibitory environment in the CNS. Many research works have …