The tumor microenvironment is a key modulator in cancer progression and has become a
novel target in cancer therapy. An increase in hyaluronan (HA) accumulation and …

Invading cancer cells adapt their migration phenotype in response to mechanical and
biochemical cues from the extracellular matrix. For instance, mesenchymal migration is …

Dendritic cells (DCs) are antigen-presenting cells capable of either activating the immune
response or inducing and maintaining immune tolerance. Understanding how biophysical …

Exposure to microgravity affects astronauts' health in adverse ways. However, less is known
about the extent to which fibroblast differentiation during the wound healing process is …

Molecules involved in crosstalk between tumor cells and fibroblasts play vital roles in tumor
progression. Extracellular matrix proteins, whose abundance is altered after being affected …

Human space travel and exploration are of interest to both the industrial and scientific
community. However, there are many adverse effects of spaceflight on human physiology. In …

Silk fibroin (SF) scaffolds have widely been used as functional materials for tissue
engineering and implantation. For long-term applications, many cross-linking strategies …

Atherosclerosis, the inflammation of artery walls due to the accumulation of lipids, is the most
common underlying cause for cardiovascular diseases. Monocytes and macrophages are …

The development of an in vitro three-dimensional (3D) culture system with cryopreserved
biospecimens could accelerate experimental research screening anticancer drugs …

Pancreatic adenocarcinoma (PAAD) is one of the most common malignant tumors with high
mortality rates and a poor prognosis. There is an urgent need to determine the molecular …