Women's health is an important and understudied area of research. The current standard of
care for many gynecological diseases such as cancer or autoimmune-linked disorders such …

Background This study aimed to develop and validate a model based on the collagen
signature and systemic immune-inflammation index to predict prognosis in rectal cancer …

Abstract The Discoidin Domain Receptors (DDRs) constitute a unique set of receptor
tyrosine kinases that signal in response to collagen. Using an inducible expression system …

Salivary gland stem cells (SGSCs) are potential cell sources for the treatment of salivary
gland diseases. The control of cell survival is an essential factor for applying stem cells to …

The use of 3D in vitro tumor models has become a common trend in cancer biology studies
as well as drug screening and preclinical testing of drug candidates. The transition from 2D …

The cytoskeleton is involved in several biological processes, including adhesion, motility,
and intracellular transport. Alterations in the cytoskeletal components (actin filaments …

Cell fate is triggered by the characteristics of the surrounding extracellular matrix (ECM)
including its composition and topological and mechanical properties. Human bone marrow …

Recent engineering technologies have transformed traditional perspectives of cancer to
include the important role of the extracellular matrix (ECM) in recapitulating the malignant …

We have efficiently produced collagen-rich microstructures in fibroblast multicellular
spheroids (MCSs) as a three-dimensional in vitro tissue analog to investigate silver (Ag) …

The trauma of central nervous system (CNS) can lead to glial scar, and it can limit the
regeneration of neurons at the injured area, which is considered to be a major factor …