[HTML][HTML] Physical network regimes of 3D fibrillar collagen networks trigger invasive phenotypes of breast cancer cells

J Sapudom, P Riedl, M Schricker, K Kroy… - Biomaterials Advances, 2024 - Elsevier
The mechanical characteristics of the extracellular environment are known to significantly
influence cancer cell behavior in vivo and in vitro. The structural complexity and viscoelastic …

The Pathological Factors Involved in Current In Vitro Atherosclerotic Models

Y Bao, H Zhang, D Wang, P Yan, S Shao… - … Engineering Part B …, 2024 - liebertpub.com
Cardiovascular disease stemmed from atherosclerosis (AS) is well recognized to be the
predominant cause of global death. To comprehensively clarify the pathogenesis of AS …

Deconstructing immune microenvironments of lymphoid tissues for reverse engineering

II Witzel, R Nasser, A Garcia‐Sabaté… - Advanced …, 2019 - Wiley Online Library
The immune microenvironment presents a diverse panel of cues that impacts immune cell
migration, organization, differentiation, and the immune response. Uniquely, both the liquid …

Construction of a 3D brain extracellular matrix model to study the interaction between microglia and T cells in co‐culture

M Frühauf, U Zeitschel, C Höfling, F Ullm… - European Journal of …, 2021 - Wiley Online Library
Neurodegenerative disorders are characterised by the activation of brain‐resident microglia
cells and by the infiltration of peripheral T cells. However, their interplay in disease has not …

Functional label-free assessment of fibroblast differentiation in 3D collagen-I-matrices using particle image velocimetry

P Riedl, T Pompe - Biomaterials Science, 2021 - pubs.rsc.org
Fibroblasts are a diverse population of connective tissue cells that are a key component in
physiological wound healing. Myofibroblasts are differentiated fibroblasts occurring in …

Fibrillar biopolymer-based scaffolds to study macrophage-fibroblast crosstalk in wound repair

F Ullm, T Pompe - Biological Chemistry, 2021 - degruyter.com
Controlled wound healing requires a temporal and spatial coordination of cellular activities
within the surrounding extracellular matrix (ECM). Disruption of cell–cell and cell–matrix …

Supramolecular Gelatin Networks Based on Inclusion Complexes

C Löwenberg, G Tripodo… - Macromolecular …, 2020 - Wiley Online Library
Hydrogel forming physical networks based on gelatin are an attractive approach toward
multifunctional biomaterials with the option of reshaping, self‐healing, and stimuli …

Phenotype Switching of Breast Cancer Cells upon Matrix Interface Crossing

P Riedl, J Sapudom, C Clemens, L Orgus… - … applied materials & …, 2023 - ACS Publications
Tumor cell growth, invasion, and metastasis are dependent on the tumor microenvironment.
Many studies emphasize a correlation between the material characteristics of the tumor …

Spatiotemporal Distribution of Mesoporous Silica Nanoparticles in Tissue-Mimicking Collagen Using Lab-on-a-Chip Technology for Drug Carrier Diffusivity Evaluation

HW Hwang, S Kim, H Hwang, HS Han… - ACS Applied Nano …, 2022 - ACS Publications
As injected drugs finally diffuse to the target cells, a quantitative understanding of the
diffusion behavior of drug molecules or drug carriers is essential for the determination of …

[图书][B] The Tumor Stroma: Biology and Therapeutics

J Prakash - 2022 - books.google.com
The identification of the role of tumor stroma—the tissue in the surroundings of cancer cells—
in cancer development, progression, and metastasis has revolutionized the fields of cancer …