Background Despite well‐recognized differences in the atherosclerotic cardiovascular
disease risk between men and women, sex differences in risk factors and sex‐specific …

Cardiovascular diseases (CVD) are the leading cause of death worldwide for both men and
women, but their prevalence and burden show marked sex differences. The existing …

The human plasma lipidome captures risk for cardiometabolic diseases. To discover new
lipid-associated variants and understand the link between lipid species and cardiometabolic …

Background—Cardiovascular disease (CVD) is the most common cause of death in the
United States and is associated with a high economic burden. Prevention of CVD focuses on …

Understanding genetic architecture of plasma lipidome could provide better insights into
lipid metabolism and its link to cardiovascular diseases (CVDs). Here, we perform genome …

Obesity and related metabolic diseases show clear sex-related differences. The growing
burden of these diseases calls for better understanding of the age-and sex-related metabolic …

Background Genetic variants within nearly 1000 loci are known to contribute to modulation
of blood lipid levels. However, the biological pathways underlying these associations are …

We integrated lipidomics and genomics to unravel the genetic architecture of lipid
metabolism and identify genetic variants associated with lipid species putatively in the …

Lipid levels are important markers for the development of cardio-metabolic diseases.
Although hundreds of associated loci have been identified through genetic association …

Background Low-density lipoprotein (LDL)-cholesterol is positively associated with
cardiovascular disease (CVD) and inversely associated with type 2 diabetes, which could …