The repair and regeneration of large bone defects resulting from disease or trauma remains a significant clinical challenge. Bioactive glass has appealing characteristics as a scaffold …
The development of reliable, synthetic scaffolds to repair large defects in load-bearing bones is one of the key challenges of regenerative medicine of hard tissues. This study …
Q Fu, E Saiz, AP Tomsia - Advanced functional materials, 2011 - Wiley Online Library
The quest for more efficient energy‐related technologies is driving the development of porous and high‐performance structural materials with exceptional mechanical strength …
LC Gerhardt, AR Boccaccini - Materials, 2010 - mdpi.com
Traditionally, bioactive glasses have been used to fill and restore bone defects. More recently, this category of biomaterials has become an emerging research field for bone …
There is a need to develop synthetic scaffolds to repair large defects in load-bearing bones. Bioactive glasses have attractive properties as a scaffold material for bone repair, but data …
A challenge in regenerating large bone defects under load is to create scaffolds with large and interconnected pores while providing a compressive strength comparable to cortical …
W Jia, GY Lau, W Huang, C Zhang… - Advanced …, 2015 - Wiley Online Library
There has been an ongoing quest for new biomedical materials for the repair and regeneration of large segmental bone defects caused by disease or trauma. Autologous …
G Kaur, V Kumar, F Baino, JC Mauro, G Pickrell… - Materials science and …, 2019 - Elsevier
The repair and restoration of bone defects in orthopaedic and dental surgery remains a major challenge despite advances in surgical procedures and post-operative treatments …
EM Valliant, JR Jones - Soft Matter, 2011 - pubs.rsc.org
There is a clinical need for materials that can stimulate repair of bone by kindling the body's own healing mechanisms. Bone can heal itself if the defect is small, but needs assistance if …