Distinct anti-inflammatory macrophage (M2) subtypes, namely M2a and M2c, are reported to
modulate the tissue repair process tightly and chronologically by modulating fibroblast …

Persistent inflammation and impaired repair in dermal wound healing are frequently
associated with cell–cell and cell–matrix miscommunication. A direct coculture model of …

Alternatively activated “M2” macrophages are believed to function during late stages of
wound healing, behaving in an anti-inflammatory manner to mediate the resolution of the …

Review on tissue repair and M1-like to M2a-like macrophages, exhibiting important
differences from in vitro phenotypes. Mp are crucial for tissue repair and regeneration but …

In normal tissue repair, macrophages exhibit a pro-inflammatory phenotype (M1) at early
stages and a pro-healing phenotype (M2) at later stages. We have previously shown that M1 …

Monocytes circulate in the bloodstream, extravasate into the tissue and differentiate into
specific macrophage phenotypes to fulfill the immunological needs of tissues. During the …

Macrophages play a key role in the wound healing process and can be divided into
classically activated macrophages (M1) and alternatively activated macrophages (M2) …

An immune response involves the action of all types of macrophages, classically activated
subtype (M1) in the early inflammatory phase and regulatory and wound-healing subtypes …

Tissue repair post injury is a multi-step wound healing process and consists of inflammatory,
proliferative, and remodeling phases, which are coordinated by interplays between many …

Human amniotic mesenchymal cells (hAMTCs) possess interesting immunomodulatory
properties, making them attractive candidates for regenerative medicine applications …