Appropriate mitochondrial physiology is an essential for health and survival. Cells have
developed unique mechanisms to adapt to stress circumstances and changes in metabolic …

In aging and neurodegenerative diseases, loss of distinct type of neurons characterizes
disease-specific pathological and clinical features, and mitochondria play a pivotal role in …

Mitochondria are cytoplasmic double-membraned organelles that are involved in a myriad of
key cellular regulatory processes. The loss of mitochondrial function is related to the …

Mitochondrial function and regulation of redox balance is fundamental in controlling cellular
life and death pathways. Antioxidants have been used to counteract disruption of redox …

Obesity is a health problem worldwide, and energy imbalance has been pointed out as one
of the main factors responsible for its development. As mitochondria are a key element in …

Organelle biogenesis is concomitant to organelle inheritance during cell division. It is
necessary that organelles double their size and divide to give rise to two identical daughter …

Mitochondria are organelles responsible for several crucial cell functions, including
respiration, oxidative phosphorylation, and regulation of apoptosis; they are also the main …

A large number of diverse mechanisms that lead to cytoprotection have been described to
date. Perhaps, not surprisingly, the role of mitochondria in these phenomena is notable. In …

In response to the energy demand triggered by developmental signals and environmental
stressors, the cells launch the mitochondrial biogenesis process. This is a self‐renewal …

Mitochondria are dynamic double-membrane bound organelles which have key roles in a
variety of cellular functions such as energy producing, regulation of calcium flux, cellular …