Luteolin-rich fraction from Perilla frutescens seed meal inhibits spike glycoprotein S1 of SARS-CoV-2-induced NLRP3 inflammasome lung cell inflammation via …

S Dissook, S Umsumarng, S Mapoung… - Frontiers in …, 2023 - frontiersin.org
Objective The multi-systemic inflammation as a result of COVID-19 can persevere long after
the initial symptoms of the illness have subsided. These effects are referred to as Long …

Hesperetin from Root Extract of Clerodendrum petasites S. Moore Inhibits SARS-CoV-2 Spike Protein S1 Subunit-Induced NLRP3 Inflammasome in A549 Lung Cells …

P Arjsri, K Srisawad, S Mapoung… - International Journal of …, 2022 - mdpi.com
Inhibition of inflammatory responses from the spike glycoprotein of SARS-CoV-2 (Spike) by
targeting NLRP3 inflammasome has recently been developed as an alternative form of …

Cyanidin-3-O-glucoside and peonidin-3-O-glucoside-rich fraction of black rice germ and bran suppresses inflammatory responses from SARS-CoV-2 spike …

W Semmarath, S Mapoung, S Umsumarng, P Arjsri… - Nutrients, 2022 - mdpi.com
Black rice is a functional food that is high in anthocyanin content, primarily C3G and P3G. It
possesses nutraceutical properties that exhibit a range of beneficial effects on human …

Garcinia kola and garcinoic acid suppress SARS‐CoV‐2 spike glycoprotein S1‐induced hyper‐inflammation in human PBMCs through inhibition of NF‐κB activation

OA Olajide, VU Iwuanyanwu… - Phytotherapy …, 2021 - Wiley Online Library
Symptoms and complications associated with severe SARS‐CoV‐2 infection such as acute
respiratory distress syndrome (ARDS) and organ damage have been linked to SARS‐CoV …

[HTML][HTML] Natural triterpenoids from licorice potently inhibit SARS-CoV-2 infection

Y Yi, J Li, X Lai, M Zhang, Y Kuang, YO Bao… - Journal of advanced …, 2022 - Elsevier
Introduction The COVID-19 global epidemic caused by severe acute respiratory syndrome
coronavirus (SARS-CoV-2) is a great public health emergency. Discovering antiviral drug …

Standardized Extract of Asparagus officinalis Stem Attenuates SARS-CoV-2 Spike Protein-Induced IL-6 and IL-1β Production by Suppressing p44/42 MAPK and Akt …

K Shirato, J Takanari, T Kizaki - Molecules, 2021 - mdpi.com
Excessive host inflammation following infection with severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is associated with severity and mortality in coronavirus disease …

Targeting spike glycoprotein S1 mediated by NLRP3 inflammasome machinery and the cytokine releases in A549 lung epithelial cells by nanocurcumin

C Chittasupho, K Srisawad, P Arjsri, R Phongpradist… - Pharmaceuticals, 2023 - mdpi.com
Chronic inflammation and tissue damage can result from uncontrolled inflammation during
SARS-CoV-2 or COVID-19 infections, leading to post-acute COVID conditions or long …

Network pharmacology reveals that resveratrol can alleviate COVID‐19‐related hyperinflammation

Z Xiao, Q Ye, X Duan, T Xiang - Disease markers, 2021 - Wiley Online Library
Hyperinflammation is related to the development of COVID‐19. Resveratrol is considered an
anti‐inflammatory and antiviral agent. Herein, we used a network pharmacological approach …

Anti-inflammatory potential of Quercetin in COVID-19 treatment

A Saeedi-Boroujeni, MR Mahmoudian-Sani - Journal of Inflammation, 2021 - Springer
SARS-CoV-2 is a betacoronavirus causing severe inflammatory pneumonia, so that
excessive inflammation is considered a risk factor for the disease. According to reports …

[HTML][HTML] RS-5645 attenuates inflammatory cytokine storm induced by SARS-CoV-2 spike protein and LPS by modulating pulmonary microbiota

T Liu, J Wu, C Han, Z Gong, G La Regina… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
An inflammatory cytokine storm is considered an important cause of death in severely and
critically ill COVID-19 patients, however, the relationship between the SARS-CoV-2 spike (S) …