Loss of normal tissue architecture is a hallmark of oncogenic transformation. In developing
organisms, tissues architectures are sculpted by mechanical forces during morphogenesis …

To establish and maintain organ structure and function, tissues need to balance stem cell
proliferation and differentiation rates and coordinate cell fate with position. By quantifying …

Tubular epithelia are a basic building block of organs and a common site of cancer
occurrence,,–. During tumorigenesis, transformed cells overproliferate and epithelial …

The physical characteristics of tumours are intricately linked to the tumour phenotype and
difficulties during treatment. Many factors contribute to the increased stiffness of tumours; …

Organ development involves complex shape transformations driven by active mechanical
stresses that sculpt the growing tissue,. Epithelial gland morphogenesis is a prominent …

Epithelium folding is a basic morphogenetic event that is essential in transforming simple
two-dimensional epithelial sheets into three-dimensional structures in both vertebrates and …

Epithelia have distinct cellular architectures which are established in development,
reestablished after wounding, and maintained during tissue homeostasis despite cell …

Biomechanical regulation of tumor phenotypes have been noted for several decades, yet the
function of mechanics in the co-evolution of the tumor epithelium and altered cancer …

Embryonic epithelia achieve complex morphogenetic movements, including in-plane
reshaping, bending and folding, through the coordinated action and rearrangement of …

The processes by which an organism develops its shape and heals wounds involve
expansion of a monolayer sheet of cells. The mechanism underpinning this epithelial …