Modeling adipogenesis: current and future perspective

HF Bahmad, R Daouk, J Azar, J Sapudom, JCM Teo… - Cells, 2020 - mdpi.com
Adipose tissue is contemplated as a dynamic organ that plays key roles in the human body.
Adipogenesis is the process by which adipocytes develop from adipose-derived stem cells …

Adipogenesis and metabolic health

AL Ghaben, PE Scherer - Nature reviews Molecular cell biology, 2019 - nature.com
Obesity is characterized by increased adipose tissue mass and has been associated with a
strong predisposition towards metabolic diseases and cancer. Thus, it constitutes a public …

[HTML][HTML] Adipose tissue plasticity from WAT to BAT and in between

YH Lee, EP Mottillo, JG Granneman - Biochimica et Biophysica Acta (BBA) …, 2014 - Elsevier
Adipose tissue plays an essential role in regulating energy balance through its metabolic,
cellular and endocrine functions. Adipose tissue has been historically classified into …

Contribution of adipogenesis to healthy adipose tissue expansion in obesity

L Vishvanath, RK Gupta - The Journal of clinical …, 2019 - Am Soc Clin Investig
The manner in which white adipose tissue (WAT) expands and remodels directly impacts the
risk of developing metabolic syndrome in obesity. Preferential accumulation of visceral WAT …

Adipogenesis: cellular and molecular aspects

B Fève - Best Practice & Research Clinical Endocrinology & …, 2005 - Elsevier
Obesity and lipoatrophy are major risks for insulin resistance, non-insulin-dependent
diabetes and cardiovascular disease. In the past three decades, significant advances have …

The developmental origins of adipose tissue

DC Berry, D Stenesen, D Zeve, JM Graff - Development, 2013 - journals.biologists.com
Adipose tissue is formed at stereotypic times and locations in a diverse array of organisms.
Once formed, the tissue is dynamic, responding to homeostatic and external cues and …

Weighing in on Adipogenesis

ER Nunn, AB Shinde, E Zaganjor - Frontiers in physiology, 2022 - frontiersin.org
Obesity is a growing health concern worldwide because of its contribution to metabolic
syndrome, type II diabetes, insulin resistance (IR), and numerous cancers. In obesity, white …

Characteristic and fate determination of adipose precursors during adipose tissue remodeling

J Ye, C Gao, Y Liang, Z Hou, Y Shi, Y Wang - Cell Regeneration, 2023 - Springer
Adipose tissues are essential for actively regulating systemic energy balance, glucose
homeostasis, immune responses, reproduction, and longevity. Adipocytes maintain dynamic …

The regulation of adipocyte growth in white adipose tissue

Q Li, KL Spalding - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Adipocytes can increase in volume up to a thousand-fold, storing excess calories as
triacylglycerol in large lipid droplets. The dramatic morphological changes required of …

Cell models and their application for studying adipogenic differentiation in relation to obesity: a review

FJ Ruiz-Ojeda, AI Rupérez, C Gomez-Llorente… - International journal of …, 2016 - mdpi.com
Over the last several years, the increasing prevalence of obesity has favored an intense
study of adipose tissue biology and the precise mechanisms involved in adipocyte …