Designer self‐assembling peptides form the entangled nanofiber networks in hydrogels by
ionic‐complementary self‐assembly. This type of hydrogel has realistic biological and …

Traditional two-dimensional (2D) cell culture systems have contributed tremendously to our
understanding of cancer biology but have significant limitations in mimicking in vivo …

The establishment of tumor microenvironment using biomimetic in vitro models that
recapitulate key tumor hallmarks including the tumor supporting extracellular matrix (ECM) is …

Bioengineered three-dimensional (3D) matrices expand our experimental repertoire to study
tumor growth and progression in a biologically relevant, yet controlled, manner. Here, we …

Cell and tissue engineering therapies for regenerative medicine as well as cell‐based
assays require an understanding of the interactions between cells with the surrounding …

Three-dimensional (3D) cell culture plays an invaluable role in tumor biology by providing in
vivo like microenviroment and responses to therapeutic agents. Among many established …

Peptide-based hydrogels have been proven to be preeminent biomedical materials due to
their high water content, tunable mechanical stability, great biocompatibility and excellent …

Natural extracellular matrix (ECM) consists of complex signals interacting with each other to
organize cellular behavior and responses. This sophisticated microenvironment can be …

Recent research has demonstrated that tumor microenvironments play pivotal roles in tumor
development and metastasis through various physical, chemical, and biological factors …

Biomedical researchers have become increasingly aware of the limitations of the
conventional 2‐D tissue cell cultures where most tissue cell studies including cancer and …