The effect of host genetics on the gut microbiome
The gut microbiome is affected by multiple factors, including genetics. In this study, we
assessed the influence of host genetics on microbial species, pathways and gene ontology …
assessed the influence of host genetics on microbial species, pathways and gene ontology …
Unravelling the effects of the environment and host genotype on the gut microbiome
To what extent do host genetics control the composition of the gut microbiome? Studies
comparing the gut microbiota in human twins and across inbred mouse lines have yielded …
comparing the gut microbiota in human twins and across inbred mouse lines have yielded …
[HTML][HTML] Host genetic control of gut microbiome composition
The gut microbiome plays a significant role in health and disease, and there is mounting
evidence indicating that the microbial composition is regulated in part by host genetics …
evidence indicating that the microbial composition is regulated in part by host genetics …
Large-scale association analyses identify host factors influencing human gut microbiome composition
A Kurilshikov, C Medina-Gomez, R Bacigalupe… - Nature …, 2021 - nature.com
To study the effect of host genetics on gut microbiome composition, the MiBioGen
consortium curated and analyzed genome-wide genotypes and 16S fecal microbiome data …
consortium curated and analyzed genome-wide genotypes and 16S fecal microbiome data …
Challenges and future directions for studying effects of host genetics on the gut microbiome
The human gut microbiome is a complex ecosystem that is involved in its host's metabolism,
immunity and health. Although interindividual variations in gut microbial composition are …
immunity and health. Although interindividual variations in gut microbial composition are …
Cross-species comparisons of host genetic associations with the microbiome
Recent studies in human populations and mouse models reveal notable congruences in gut
microbial taxa whose abundances are partly regulated by host genotype. Host genes …
microbial taxa whose abundances are partly regulated by host genotype. Host genes …
Association of host genome with intestinal microbial composition in a large healthy cohort
Intestinal microbiota is known to be important in health and disease. Its composition is
influenced by both environmental and host factors. Few large-scale studies have evaluated …
influenced by both environmental and host factors. Few large-scale studies have evaluated …
[HTML][HTML] Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort
Human genetic variation affects the gut microbiota through a complex combination of
environmental and host factors. Here we characterize genetic variations associated with …
environmental and host factors. Here we characterize genetic variations associated with …
Host genetics and gut microbiome: challenges and perspectives
The mammalian gut is colonized by trillions of microorganisms collectively called the
microbiome. It is increasingly clear that this microbiome has a critical role of in many aspects …
microbiome. It is increasingly clear that this microbiome has a critical role of in many aspects …
[HTML][HTML] Host genetic variation impacts microbiome composition across human body sites
R Blekhman, JK Goodrich, K Huang, Q Sun… - Genome biology, 2015 - Springer
Background The composition of bacteria in and on the human body varies widely across
human individuals, and has been associated with multiple health conditions. While microbial …
human individuals, and has been associated with multiple health conditions. While microbial …