Periodic oscillations play an important role in many biomedical systems. Proper functioning
of biological systems that respond to periodic signals requires the ability to synchronize with …

The sequencing of genomes of several organisms and advances in high throughput
technologies for transcriptome and proteome analysis has allowed detailed mechanistic …

Understanding the mechanisms behind translation and its rate-limiting steps is crucial for
both the development of drug targets and improvement of heterologous protein production …

Gene translation is a central process in all living organisms. Developing a better
understanding of this complex process may have ramifications to almost every biomedical …

Translation of mRNA into protein is a fundamental yet complex biological process with
multiple factors that can potentially affect its efficiency. Here, we study a stochastic model …

A central biological process in all living organisms is gene translation. Developing a deeper
understanding of this complex process may have ramifications to almost every biomedical …

Background In prokaryotes, transcription and translation are dynamically coupled, as the
latter starts before the former is complete. Also, from one transcript, several translation …

Computational modelling of in vivo protein synthesis is highly complicated, as it requires the
simulation of ribosomal movement over the entire transcriptome, as well as consideration of …

Gene translation is a central stage in the intracellular process of protein synthesis. Gene
translation proceeds in three major stages: initiation, elongation, and termination. During the …

Gene expression is a fundamental cellular process by which proteins are synthesized based
on the information coded in the genes. The two major steps of this process are the …