Effect of preconditioning ischemia on reperfusion arrhythmias after coronary artery occlusion and reperfusion in the rat.

JM Hagar, SL Hale, RA Kloner - Circulation research, 1991 - Am Heart Assoc
Severe arrhythmias occur predictably on reperfusion after 5 minutes of coronary occlusion in
the rat. There is little data available on whether ischemic preconditioning (PC) of hearts can …

Enalapril prevents cardiac fibrosis and arrhythmias in hypertensive rats.

M Pahor, R Bernabei, A Sgadari, G Gambassi Jr… - …, 1991 - Am Heart Assoc
To evaluate the effects of hypertension on cardiac hypertrophy, on myocardial structure, and
on ventricular arrhythmias, 27 3-month-old spontaneously hypertensive rats were treated …

Effect of BN 50739, a new platelet activating factor antagonist, on ischaemia induced ventricular arrhythmias in isolated working rat hearts

M Koltai, A Tosaki, D Hosford, A Esanu… - Cardiovascular …, 1991 - academic.oup.com
Study objective–The aim was to investigate the role of platelet activating factor (paf) in
myocardial ischaemia by using BN 50739, a new specific paf receptor antagonist with a …

Antiarrhythmic properties of tedisamil (KC8857), a putative transient outward K+ current blocker.

GN Beatch, S Abraham, BA MacLeod… - British journal of …, 1991 - ncbi.nlm.nih.gov
Rats were used to evaluate the antiarrhythmic properties of tedisamil, a novel agent with the
electrophysiological properties of a Class III antiarrhythmic drug. Tedisamil was tested …

Omega-3 PUFA's reduce the vulnerability of the rat heart to ischaemic arrhythmia in the presence of a high intake of saturated animal fat

JS Charnock, PL McLennan, K Sundram… - Nutrition Research, 1991 - Elsevier
The effect of dietary lipids upon the development of cardiac arrhythmias has been studied in
an animal model of Sudden Cardiac Death. Ischaemic arrhythmia in mature male rats was …

Torsades de pointes: arrhythmia, syndrome, or chimera? A perspective in the light of the Lambeth Conventions

MJ Curtis - Cardiovascular drugs and therapy, 1991 - Springer
What is torsades de pointes? Is it an arrhythmia or a syndrome? The distinction is critical. In
this article I have attempted to explain why this is so. Both from the clinical and nonclinical …

Protective effects of D, L-carnitine against arrhythmias induced by lysophosphatidylcholine or reperfusion

J Duan, MP Moffat - European journal of pharmacology, 1991 - Elsevier
Electrophysiological effects of lysophosphatidylcholine (50 or 100 μM) and D, L-carnitine
(100 μM) were studied under control conditions and in response to simulated ischaemia and …

Lack of significant effects of superoxide dismutase and catalase on development of reperfusion arrhythmias

JM Hagar, SL Hale, JP Ilvento, RA Kloner - Basic research in cardiology, 1991 - Springer
It has been reported that agents having the ability to scavenge oxygen-derived free radicals
reduce the severity of ventricular arrhythmias that occur after brief coronary occlusion and …

Pharmacological studies of arrhythmias induced by rose bengal photoactivation

M Bernier, Y Kusama, M Borgers, L Ver Donck… - Free Radical Biology …, 1991 - Elsevier
Singlet oxygen and superoxide production by rose bengal photoactivation leads to rapid
electrophysiological changes and arrhythimias. To investigate which intermediate is …

Effects of Org 7797 on early, late and inducible arrhythmias following coronary artery occlusion in rats and dogs.

E Winslow, JK Campbell, E Barron… - British journal of …, 1991 - ncbi.nlm.nih.gov
The class Ic steroidal antiarrhythmic agent, Org 7797, was compared with two other Ic
agents, flecainide and propafenone for intravenous activity against ischaemia-related …