Seven receptors with highly homologous structural features have recently been discovered
that belong to a new family of seven membrane-spanning receptors within the G-protein …

Potentiation of glucose-induced insulin secretion by intestinal factors has been described for
many years. Today, two major peptides with potent insulinotropic action have been …

Corticotropin-releasing factor (CRF) is the principal neuroregulator of the hypothalamic-
pituitary-adrenocortical axis and plays an important role in coordinating the endocrine …

THE two forms of pituitary adenylyl cyclase-activating polypeptide (PACAP-27 and-38) are
neuropeptides of the secretin/glucagon/vasoactive intestinal polypeptide/growth-hormone …

The growth hormone–releasing hormone receptor (GHRHR) is a member of the family of G
protein–coupled receptors that is expressed on pituitary somatotrope cells and mediates the …

We have identified and characterized cDNAs encoding a novel receptor that is a member of
a distinct class of seven transmembrane helix, C,-coupled receptors. This receptor mediates …

Glucagon and the glucagon receptor are a primary source of control over blood glucose
concentrations and are especially important to studies of diabetes in which the loss of …

We have cloned and sequenced a cDNA (RPR4) encoding a new member of the
secretin/calcitonin/parathyroid hormone (PTH) receptor family. RPR4 was identified by PCR …

Pituitary adenylate cyclase-activating polypeptide (PACAP), a neuropeptide belonging to the
vasoactive intestinal peptide (VIP)/secretion/glucagon family of peptides, interacts with a …

Corticotrophin‐releasing factor (CRF) is the principal hypothalamic factor governing the
pituitary‐adrenal axis, but the wide extra‐pituitary distribution of CRF and its receptors …