Discusses free radicals in the human body and their role in the emergence of diseases.
Radicals generated in the body; How radicals react; Evolution of antioxidant defenses in the …

We argue for the critical role of oxidative damage in causing the mitochondrial dysfunction of
aging. Oxidants generated by mitochondria appear to be the major source of the oxidative …

Free radicals and other oxygen-derived species are constantly generated in vivo, both by
“accidents of chemistry” and for specific metabolic purposes. The reactivity of different free …

REPAIR OF OXIDATIVE DAMAGE TO DNA: Enzymology and Biology Page 1 Annu. Rev.
Biochem. 1994. 63:915-48 Copyright © 1994 by Annual Reviews Inc. All rights reserved …

Free radicals and other reactive oxygen species (ROS) are constantly formed in the human
body, often for useful metabolic purposes. Antioxidant defenses protect against them, but …

The occurrence of reactive oxygen species (ROS), termed as prooxidants, is a characteristic
of normal aerobic organisms. The term “reactive oxygen species” collectively denotes …

The role of the YAP1 transcription factor in the response of Saccharomyces cerevisiae cells
to a variety of conditions that induce oxidative stress has been investigated. Cells deficient in …

During the past 25 years, the field of free radical biology has germinated sprouted, and
flowered. Free radicals derived from molecular oxygen, formerly of interest only to radiation …

Green plants, within certain limitations, can adapt to a wide variety of unfavourable
conditions such as drought, temperature changes, light variations, infectious attacks, air …

The activity of the enzymes involved in the antioxidant defence—superoxide dismutase
(SOD), glutathione peroxidase (GPx), reductase (GR) S-transferase (GST)—as well as the …