Comparison of tests and sample size formulae for proving therapeutic equivalence based on the difference of binomial probabilities
P Roebruck, A Kühn - Statistics in Medicine, 1995 - Wiley Online Library
To prove the hypothesis that a new treatment is as effective as a standard one, a possibility
is to test the one‐sided null hypothesis of a clear inferiority of the new treatment against the …
is to test the one‐sided null hypothesis of a clear inferiority of the new treatment against the …
Sample size determination in stratified trials to establish the equivalence of two treatments
JM Nam - Statistics in Medicine, 1995 - Wiley Online Library
When designing a trial to establish that a new treatment is as effective as a standard one, the
conventional test procedure and sample size based on a null hypothesis of no difference …
conventional test procedure and sample size based on a null hypothesis of no difference …
Similarity/equivalence trials for combination vaccines.
WC Blackwelder - Annals of the New York Academy of Sciences, 1995 - europepmc.org
In a similarity or" equivalence" trial of a combination vaccine, we wish to show that the
combination is sufficiently similar to the separately administered components in some …
combination is sufficiently similar to the separately administered components in some …
A randomised, multinational study with sequential therapy comparing ciprofloxacin twice daily and ofloxacin once daily.
H Bassaris, E Akalin, S Calangu, R Kitzes, J Kosmidis… - Infection, 1995 - europepmc.org
In a multinational, open, randomised, controlled clinical study, 474 hospitalised patients with
moderate or severe infections were treated with sequential regimens of ofloxacin or …
moderate or severe infections were treated with sequential regimens of ofloxacin or …
Roxatidine versus ranitidine in the treatment of duodenal ulcers: A randomized double‐blind controlled multicentre study in Singapore
KM Fock, JY Kang, HS Ng, TM Ng… - Journal of …, 1995 - Wiley Online Library
Roxatidine acetate, a new H2 receptor antagonist, was compared with ranitidine in the
treatment of duodenal ulcers in a double‐blind multicentre study. Eighty‐four patients with …
treatment of duodenal ulcers in a double‐blind multicentre study. Eighty‐four patients with …
Roxatidine versus ranitidine in the short-term management of duodenal ulcer: a randomized, double-blind trial
FY Chang, CT Lee, WW Ng, SD Lee… - Current therapeutic …, 1995 - Elsevier
Roxatidine is a structurally novel histamine2-receptor antagonist. This randomized, double-
blind trial compared duodenal ulcer healing rates after 4 and 8 weeks of treatment with a …
blind trial compared duodenal ulcer healing rates after 4 and 8 weeks of treatment with a …
Randomisierte, multinationale Studie mit einer sequentiellen Therapie, die Ciprofloxacin zweimal täglich mit Ofloxacin einmal täglich vergleicht
P Bassaris, E Akalin, S Calangu, R Kitzes, J Kosmidis… - Infection, 1995 - Springer
In a multinational, open, randomised, controlled clinical study, 474 hospitalised patients with
moderate or severe infections were treated with sequential regimens of ofloxacin or …
moderate or severe infections were treated with sequential regimens of ofloxacin or …