With a cat model of regional cardiac ischemia, we examined whether the incidence of
reperfusion-induced ventricular fibrillation (VF) could be reduced by ventricular premature …

This study tested the hypothesis that in vivo antiarrhythmic effects of dietary fish oil can be
attributed directly to changes in myocardial properties. Sixty adult male rats were fed a fish …

Background Brief myocardial ischemia is associated with myocardial and coronary
endothelial dysfunction caused by oxygen free radicals released during reperfusion …

Magnolol is an active component of Magnolia officinalis. It is 1000‐times more potent than α‐
tocopherol in inhibiting lipid peroxidation in rat heart mitochondira. In the present study, the …

NO has been implicated in the mechanism of ischaemic preconditioning. To verify this
hypothesis further we have attempted to reproduce effects of ischaemic preconditioning by …

Background Cardiac reperfusion initiates release of inositol 1, 4, 5-triphosphate [Ins (1, 4, 5)
P3] and arrhythmogenesis via norepinephrine stimulation of α1-adrenergic receptors. The …

1 Bacterial endotoxin (lipopolysaccharide derived from Escherichia coli) was injected
intraperitoneally in conscious rats in doses ranging from 0.5 to 2.5 mg kg− 1. At various …

Oxyradicals have been implicated as a possible cause of postischemic reperfusion
arrhythmias (RA). However, the ability of enzymatic scavengers such as superoxide …

To assess the role of reactive oxygen species and nitric oxide (NO) in the genesis of
reperfusion-induced arrhythmias, the effects of reactive oxygen species scavengers and NO …

In a model of ventricular arrhythmias of central origin, we investigated the effects of
rilmenidine, an oxazoline with antihypertensive properties, and idazoxan, an imidazoline …