I. Introduction T HE calcitonin (CT) and calcitonin gene-related peptide (CGRP) are derived
from the CT/CGRP gene, which is localized in chromosome 11. Alternative splicing of the …

Receptors for VIP, PACAP, secretin, GRF, glucagon, GLP-1, and other members of their new
family of G protein-linked receptors: structure-function relationship with special reference to the …

CD97 is an activation-induced antigen on leukocytes with a seven-span transmembrane (7-
TM) region homologous to the secretin receptor superfamily. However, in contrast to this …

Calcitonin gene-related peptide (CGRP) is a neuropeptide with diverse biological effects
including potent vasodilator activity. We report here the cloning of a complementary DNA …

Alternative splicing of two exons of the rat pituitary adenylate cyclase activating polypeptide
(PACAP) receptor gene generates four major splice variants that are differentially expressed …

Calcitonin (CT) and parathyroid hormone (PTH), whose receptors belong to the same family
of G protein-coupled receptors, share no amino acid sequence homology and selectively …

Pituitary adenylate cyclase-activating polypeptide (PACAP) is a novel neuropeptide that
produces its biological effects by interacting with G protein-coupled receptors. Molecular …

Most of the bone and kidney-related functions of parathyroid hormone (PTH) and
parathyroid hormone-related peptide (PTHrP) are thought to be mediated by the PTH/PTHrP …

The recent cDNA cloning of three cell-surface molecules has identified a subfamily of
leukocyte proteins that are characterized by the presence of tandemly repeated extracellular …

Distinct themes exist for ligand-binding domains of G protein-coupled receptors. The
secretin receptor is prototypic of a recently described family in this superfamily which binds …