A generalized modeling framework for process synthesis alternatives is proposed, based on
fundamental mass/heat‐transfer principles. A multipurpose mass/heat‐transfer module is …

This paper presents first a brief overview of the considerable work that has been performed
for the systematic synthesis of process flowsheets and corresponding subsystems. Next, it is …

This paper describes the synthesis of distillation sequences simultaneously with the
synthesis of other process subsystems. An improved MINLP approach is proposed for the …

This paper presents an overview of the mathematical programming approach for process
synthesis. First, the methods for process synthesis are reviewed with an emphasis on …

In the field of process synthesis, heat integration methodologies have been matured
considerably during the past two decades. Today, these techniques are widely accepted as …

An extended vertical MILP model is proposed for selecting Heat Load Distributions (HLD=
set of matches and corresponding duties) that will give networks with close to minimum area …

The algorithm for global optimization of heat exchanger networks by Quesada and
Grossmann [171 has been extended to multi period operation for fixed configuration. Under …

A systematic approach based on few heuristics for the synthesis of optimum heat exchanger
networks has been developed. The approach, which is simple and easy to apply, consists of …

A new index, called Design Resiliency Index, which numerically indicates the size of
feasible region in terms of uncertain source-temperature or flowrates for the fixed design …

This thesis deals with Generalized Disjunctive Programming (GDP) models and solution
techniques for the optimization of process flowsheets. GDP is a natural framework for …