OBJECTIVES: This study examined whether there is a risk that tetanus-toxoid-containing
vaccines could cause Guillain-Barré syndrome and, if so, how large the risk is. METHODS …

In 1988 a committee of the Institute of Medicine of the National Academy of Sciences
suggested that a sequential inactivated poliovirus vaccine (IPV)-oral poliomyelitis vaccine …

The relative immunity induced by sequential administration of inactivated poliovirus vaccine
(IPV) produced in human diploid cells and live attenuated oral poliovirus vaccine (OPV) was …

To estimate age-specific incidences and assess the national morbidity and mortality burden
for Guillain-Barre syndrome (GBS) in the United States, a national hospital discharge …

Attenuated strains of the Sabin oral poliovirus vaccine replicate in the human gut and in rare
cases cause vaccine-associated paralytic poliomyelitis (VAPP). Reversion of vaccine strains …

To detect less prevalent viruses, such as wild-type polioviruses in sewage from a highly
immunized community, a method was developed to efficiently recover viruses and remove …

Significant progress is being made towards the global eradication of poliomyelitis by the
year 2000. The strategies recommended by the World Health Organization for polio …

A change in the recommendations for routine immunization of children is indicated because
of the reduced risk of exposure to wild-type polio viruses and the continued occurrence of …

Background. Advisory committees have recommended the increased use of inactivated
poliovirus vaccine (IPV) for children. Objectives. The purpose of this study was to assess the …

Paralytic poliomyelitis has plagued mankind for centuries. The incidence of acute paralytic
poliomyelitis dramatically declined in 1955 only after the introduction of the inactivated polio …