The role of macrophages in Wallerian degeneration

W Brück - Brain pathology, 1997 - Wiley Online Library
The present review focuses on macrophage properties in Wallerian degeneration. The
identification of hematogenous phagocytes, the involvement of cell surface receptors and …

Transient suppression of macrophage functions by liposome-encapsulated drugs

N van Rooijen, J Bakker, N Sanders - Trends in biotechnology, 1997 - cell.com
Macrophages play an important role in host defense reactions, for example, by phagocytosis
of particulate materials. This process also results in the rapid removal of targeting devices …

Clodronate and liposome‐encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5′‐(β, γ‐dichloromethylene) triphosphate, by mammalian cells …

JC Frith, J Mönkkönen, GM Blackburn… - Journal of Bone and …, 1997 - academic.oup.com
Clodronate, alendronate, and other bisphosphonates are widely used in the treatment of
bone diseases characterized by excessive osteoclastic bone resorption. The exact …

Alveolar macrophages are required for protective pulmonary defenses in murine Klebsiella pneumonia: elimination of alveolar macrophages increases neutrophil …

E Broug-Holub, GB Toews, JF Van Iwaarden… - Infection and …, 1997 - Am Soc Microbiol
To study the in vivo role of alveolar macrophages (AM) in gram-negative bacterial
pneumonia in mice, AM were eliminated by the intratracheal (it) administration of …

Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ

G Wolff, S Worgall, N van Rooijen, WR Song… - Journal of …, 1997 - Am Soc Microbiol
Based on the hypothesis that tissue macrophages present an obstacle for adenovirus (Ad)
vector-mediated gene transfer to internal organs, this study evaluated the consequences of …

Crucial role of marginal zone macrophages and marginal zone metallophils in the clearance of lymphocytic choriomeningitis virus infection

P Seiler, P Aichele, B Odermatt… - European journal of …, 1997 - Wiley Online Library
Macrophages play a key role in the immune defense against pathogens. They control early
invasion by antigen‐unspecific phagocytosis of pathogens and act as professional antigen …

Colony-stimulating factor-1 plays a major role in the development of reproductive function in male mice

PE Cohen, MP Hardy, JW Pollard - Molecular Endocrinology, 1997 - academic.oup.com
Abstract Colony-stimulating factor-1 (CSF-1) is the principal regulator of cells of the
mononuclear phagocytic lineage that includes monocytes, tissue macrophages, microglia …

[HTML][HTML] Biodistribution of liposomes containing synthetic galactose-terminated diacylglyceryl-poly (ethyleneglycol) s

K Shimada, JAAM Kamps, J Regts, K Ikeda… - … et Biophysica Acta (BBA …, 1997 - Elsevier
We describe the synthesis of biodegradable poly (ethyleneglycol)-coupled galactolipids in
which the galactose moiety is separated from a diacylglyceride lipid anchor by poly …

Alveolar macrophages regulate the induction of primary cytotoxic T-lymphocyte responses during influenza virus infection

OL Wijburg, S DiNatale, JIM Vadolas… - Journal of …, 1997 - Am Soc Microbiol
Virus-specific cytotoxic T lymphocytes (CTL) are thought to be responsible for the
eradication of respiratory influenza virus infections by direct cytolysis of virus-infected …

Diagnosis and treatment of cell proliferative disease having clonal macrophage involvement

MS McGrath, B Herndier, B Shiramizu - US Patent 5,639,600, 1997 - Google Patents
The presence of clonal macrophages in pre-cancerous and cancerous tissue represents an
early stage of the disease in which clonal expansion of macrophages occurs due to HIV …