The nagging question of the function ofN-acetylaspartylglutamate

JT Coyle - Neurobiology of disease, 1997 - Elsevier
N-Acetylaspartylglutamate (NAAG) is a neuropeptide found in millimolar concentrations in
brain that is localized to subpopulations of glutamatergic, cholinergic, GABAergic, and …

Monoclonal antibodies to the extracellular domain of prostate-specific membrane antigen also react with tumor vascular endothelium

H Liu, P Moy, S Kim, Y Xia, A Rajasekaran, V Navarro… - Cancer research, 1997 - AACR
Prostate-specific membrane antigen (PSMA), initially defined by monoclonal antibody (mAb)
7E11, is a now well-characterized type 2 integral membrane glycoprotein expressed in a …

Characterization and glutamyl preferring carboxypeptidase function of prostate specific membrane antigen: a novel folate hydrolase

WDW Heston - Urology, 1997 - Elsevier
We have cloned the gene encoding the prostate-specific membrane (PSM) antigen, which is
recognized by the 7E11C-5 antibody. The antigen is strongly expressed in prostate cancer …

Molecular Cloning of a Peptidase Against N‐Acetylaspartylglutamate from a Rat Hippocampal cDNA Library

T Bzdega, T Turi, B Wroblewska, D She… - Journal of …, 1997 - Wiley Online Library
N‐Acetylaspartylglutamate (NAAG) is the most prevalent peptide neurotransmitter in the
mammalian nervous system. NAAG selectively activates the type 3 metabotropic glutamate …

Structure of membrane glutamate carboxypeptidase

ND Rawlings, AJ Barrett - Biochimica et Biophysica Acta (BBA)-Protein …, 1997 - Elsevier
Membrane glutamate carboxypeptidase (mGCP) hydrolyses pteroylpoly-γ-glutamates,
methotrexate tri-γ-glutamate and N-acetyl-aspartyl-α-glutamate. The enzyme is thought to be …

Monoclonal antibody 7E11. C5 staining of viable LNCaP cells

RJ Barren III, EH Holmes, AL Boynton… - The …, 1997 - Wiley Online Library
Background Prostate‐specific membrane antigen (PSMA) is a transmembrane glycoprotein
defined by the monoclonal antibody 7E11. C5. The 7E11. C5 antibody forms the basis of an …

Cloning and characterization of a novel peptidase from rat and human ileum

BL Shneider, S Thevananther, MS Moyer… - Journal of Biological …, 1997 - ASBMB
A novel 100-kDa ileal brush border membrane protein (I100) has been purified by anionic
glycocholate affinity chromatography. Polyclonal antibodies raised against this protein were …