Ischemic preconditioning: exploring the paradox

K Przyklenk, RA Kloner - Progress in cardiovascular diseases, 1998 - Elsevier
Brief transient episodes of nonlethal myocardial ischemia protect or “precondition” the heart
and render the myocardium resistant to a subsequent more sustained ischemic insult. The …

Ischaemic preconditioning: mechanisms and potential clinical applications

A Hawaleshka, E Jacobsohn - Canadian journal of anaesthesia, 1998 - Springer
Purpose Brief ischaemic episodes, followed by periods of reperfusion, increase the
resistance to further ischaemic damage. This response is called “ischaemic …

Medical and cellular implications of stunning, hibernation, and preconditioning: an NHLBI workshop

RA Kloner, R Bolli, E Marban, L Reinlib, E Braunwald - Circulation, 1998 - Am Heart Assoc
On July 2–3, 1996, the National Heart, Lung, and Blood Institute sponsored a workshop in
Columbia, Md, entitled “The Medical and Cellular Implications of Myocardial Stunning …

Parasympathetic tone affects electrocardiographic preconditioning during right coronary angioplasty

Y Tsuchiya, T Nii, K Shirai, K Saku, K Arakawa - Cardiology, 1998 - karger.com
We investigated whether parasympathetic tone may affect ischemic preconditioning in terms
of ST segment alteration during coronary angioplasty. Coronary balloon angioplasty was …

Angina: Who needs it? Cardioprotection in the preconditioning era

A Dana, DM Yellon - Cardiovascular drugs and therapy, 1998 - Springer
Over the past two decades, it has been demonstrated in various animal species that the
myocardium possesses innate adaptive mechanisms that may render it more resistant to …

Phentolamine and preconditioning during coronary angioplasty

A Dana, J Imagawa, DM Yellon - Circulation, 1998 - Am Heart Assoc
A primary rhythm in the central nervous system that entrains both heart rate, blood pressure,
and ventilation1 is suggested by profound effects on angina through consciously focusing …

Adenosine, KATP Channel, and Cardioprotection in the Intact Heart

DW Green, GJ Grover - Cardiovascular Biology of Purines, 1998 - Springer
Recent breakthroughs in our understanding of the endogenous defense mechanisms of the
heart to ischemia have made it possible to develop novel and efficacious therapeutics for …

Acute Myocardial Infarction

KA Spratt, TY Huehns, RL Wilensky - Unstable Coronary Artery …, 1998 - Springer
Each year in the United States alone, one and a half million patients suffer an acute
myocardial infarction while the annual cost for the prevention and treatment of this illness is …

Pharmacological Modification of Ischemic Preconditioning During Percutaneous Transluminal Coronary Angioplasty

T Ueda, K Hashimura, Y Matsu-Ura, Y Kato… - The Ischemic Heart, 1998 - Springer
In the progression of repetitive balloon inflations during percutaneous transluminal coronary
angioplasty (PTCA), the heart becomes more tolerant to ischemia. The study reported here …