Prostate-specific membrane antigen expression is greatest in prostate adenocarcinoma and lymph node metastases

SD Sweat, A Pacelli, GP Murphy, DG Bostwick - Urology, 1998 - Elsevier
Objectives. Prostate-specific membrane antigen (PSMA) is an integral membrane protein
highly specific for the prostate. PSMA may be clinically useful for predicting outcome in …

Current evaluation of the tissue localization and diagnostic utility of prostate specific membrane antigen

GP Murphy, AAA Elgamal, SL Su… - … Journal of the …, 1998 - Wiley Online Library
BACKGROUND Current statistics indicate that prostate carcinoma is the most common form
of cancer diagnosed in American men, resulting in the second highest cancer death rate …

Constitutive and antibody-induced internalization of prostate-specific membrane antigen

H Liu, AK Rajasekaran, P Moy, Y Xia, S Kim, V Navarro… - Cancer research, 1998 - AACR
Prostate-specific membrane antigen (PSMA) is a cell surface glycoprotein expressed
predominantly by prostate cancer cells. We have characterized four monoclonal antibodies …

Mapping, genomic organization and promoter analysis of the human prostate-specific membrane antigen gene

DS O'Keefe, SL Su, DJ Bacich, Y Horiguchi… - … et Biophysica Acta (BBA …, 1998 - Elsevier
Prostate-specific membrane antigen (PSMA) is a 100 kDa type II transmembrane protein
with folate hydrolase and NAALAdase activity. PSMA is highly expressed in prostate cancer …

Folylpoly-γ-glutamate carboxypeptidase from pig jejunum: molecular characterization and relation to glutamate carboxypeptidase II

CH Halsted, E Ling, R Luthi-Carter… - Journal of Biological …, 1998 - ASBMB
Jejunal folylpoly-γ-glutamate carboxypeptidase hydrolyzes dietary folates prior to their
intestinal absorption. The complete folylpoly-γ-glutamate carboxypeptidase cDNA was …

Molecular characterization of human brain N-acetylated α-linked acidic dipeptidase (NAALADase)

R Luthi-Carter, AK Barczak, H Speno… - Journal of Pharmacology …, 1998 - ASPET
N-Acetylated α-linked acidic dipeptidase (NAALADase) is a neuropeptidase that may
modulate glutamatergic neurotransmission. Independent of its characterization in the …

Isolation and expression of a rat brain cDNA encoding glutamate carboxypeptidase II

R Luthi-Carter, UV Berger… - Proceedings of the …, 1998 - National Acad Sciences
N-acetylated alpha-linked acidic dipeptidase (NAALADase) hydrolyzes acidic peptides,
such as the abundant neuropeptide N-acetyl-α-l-aspartyl-l-glutamate (NAAG), thereby …

[HTML][HTML] Hydrolysis of the neuropeptide N-acetylaspartylglutamate (NAAG) by cloned human glutamate carboxypeptidase II

R Luthi-Carter, AK Barczak, H Speno, JT Coyle - Brain research, 1998 - Elsevier
Glutamate carboxypeptidase II may modulate excitatory neurotransmission through the
catabolism of the neuropeptide N-acetylaspartylglutamate (NAAG) and possibly other …

Capromab pendetide: a review of its use as an imaging agent in prostate cancer

HM Lamb, D Faulds - Drugs & aging, 1998 - Springer
Capromab pendetide, radiolabelled with indium-111, is a radioimmunoscintigraphic imaging
agent used in patients with prostate cancer. It consists of a murine monoclonal antibody …

Characterization of human cellular γ-glutamyl hydrolase

MS Rhee, B Lindau-Shepard, KJ Chave, J Galivan… - Molecular …, 1998 - ASPET
A previously identified cDNA encoding a human γ-glutamyl hydrolase was expressed in a
baculovirus system. The expressed protein had molecular mass of 37 kDa. Treatment of the …