We studied IL‐4, IL‐10 and IFN‐γ secretion by splenocytes and the plasma levels of different
isotypes of antibodies against various antigens of Trypanosoma congolense in highly …

Using in situ hybridization and immunohistochemistry the induction of potential cytokines
[interleukin 1β (IL-1β), IL-4, IL-6, IL-10, tumour necrosis factor α (TNF-α), interferon γ (IFN-γ) …

The activated 20 S proteasome, which has been found only in mammalian cells, is
composed of two heptamer rings of an activator protein on each end of the 20 S proteasome …

African sleeping sickness is characterized by a number of distinct neurological symptoms,
which include dysaesthesia, extrapyramidal motor disturbances, disruption of sleep, as well …

Microglial cells play a key role in the events triggered by infection, injury or degeneration in
the central nervous system not only as scavenger cells but also as immune effector …

We have investigated the possibility that nitric oxide (NO) synthesis may affect the course of
a trypanosome infection via T-cell responses using mice deficient in inducible NO synthase …

The flagellar pocket of African trypanosomes is a critical sorting station for protein and
membrane trafficking, and is considered to be an Achilles' heel of this deadly pathogen …

Drug treatment of late-stage human African Trypanosomiasis (HAT) in which the central
nervous system (CNS) is involved may be complicated by a severe post-treatment reactive …

Trypanosoma brucei brucei (Tbb) infection is a model of chronic immune response
associated with severe neurological disorders believed to lead to coma and death. We …

Les trypanosomes africains, dont la plupart sont transmis par les glossines ou mouches
tsétsé, déterminent à la fois la maladie du sommeil et des affections d'une grande …