Exercise provides direct biphasic cardioprotection via manganese superoxide dismutase activation

N Yamashita, S Hoshida, K Otsu, M Asahi… - The Journal of …, 1999 - rupress.org
Epidemiologic investigations have shown that exercise reduces morbidity and mortality from
coronary artery disease. In this study, using a rat model, we attempted to determine whether …

Adaptation to high altitude hypoxia protects the rat heart against ischemia-induced arrhythmias. Involvement of mitochondrial KATPChannel

G Asemu, F Papoušek, B Ošťádal, F Kolář - Journal of molecular and …, 1999 - Elsevier
The aim was to determine whether adaptation to chronic hypoxia protects the heart against
ischemic arrhythmias and whether ATP-dependent potassium channels (KATP) play a role …

Sympathetic activation triggers ventricular arrhythmias in rat heart with chronic infarction and failure

XJ Du, HS Cox, AM Dart, MD Esler - Cardiovascular research, 1999 - academic.oup.com
Objective: To seek direct evidence for a cause–effect relation between sympathetic
activation and arrhythmogenesis. Methods: Rats underwent open-chest surgery with either …

Protective effect of Crataegus oxyacantha against reperfusion arrhythmias after global no-flow ischemia in the rat heart

S Al Makdessi, H Sweidan, K Dietz, R Jacob - Basic research in cardiology, 1999 - Springer
The protective effect against reperfusion arrhythmias of a 3-month oral pretreatment with a
dried extract of Crataegus oxyacantha (LI 132)(standardized to 2.2% flavonoids) was …

Different sympathovagal modulation of heart rate during social and nonsocial stress episodes in wild-type rats

A Sgoifo, JM Koolhaas, E Musso, SF De Boer - Physiology & behavior, 1999 - Elsevier
The acute consequences of a social aversive stimulus (defeat) on the autonomic control
upon the electrical activity of the heart were measured and compared to those observed in …

Antiarrhythmic Effect of Magnolol and Honokiol during Acute Phase of Coronary Occlusion in Anesthetized Rats: Influence of L-NAME and Aspirin

SK Tsai, CH Huang, SS Huang, LM Hung, CY Hong - Pharmacology, 1999 - karger.com
This study was designed to evaluate the in vivo effect of magnolol and honokiol on the acute
phase of coronary ligation in the presence of nitric oxide inhibitor (L-NAME) or …

Orally administered NHE1 inhibitor cariporide reduces acute responses to coronary occlusion and reperfusion

RA Humphreys, JV Haist… - American Journal …, 1999 - journals.physiology.org
Na+/H+ exchange (NHE) mediates myocardial ischemic and reperfusion injury. We
examined the effects of dietary administration of the potent and selective NHE1 inhibitor …

Ischemia/reperfusion-induced arrhythmias in anaesthetized rats: a role of Na+ and Ca2+ influx

HR Lu, P Yang, P Remeysen, A Saels… - European journal of …, 1999 - Elsevier
We hypothesized that by limiting the Na+ and Ca2+ loading by a blocker/inhibitor of the Na+
channel (lidocaine), Na+ overload (R56865: N-[1-[4-(4-fluorophenoxy) butyl]-4-piperidinyl]-N …

Myocardial damage due to ischemia and reperfusion in hypertriglyceridemic and hypertensive rats: participation of free radicals and calcium overload

K Carvajal, M El Hafidi, G Baños - Journal of hypertension, 1999 - journals.lww.com
Objective In a model of hypertriglyceridemia and hypertension in rats (HTG), induced by
adding refined sugar to the animals' drinking water, we investigated the response to an …

[HTML][HTML] Novel cardiac protective effects of urea: from shark to rat

X Wang, L Wu, M Aouffen, MA Mateescu… - British journal of …, 1999 - ncbi.nlm.nih.gov
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