Agrin is a major heparan sulfate proteoglycan accumulating in Alzheimer's disease brain

MM Verbeek, I Otte-Höller, J Van Den Born… - The American journal of …, 1999 - Elsevier
Heparan sulfate proteoglycans (HSPGs) have been suggested to play an important role in
the formation and persistence of senile plaques and neurofibrillary tangles in dementia of …

Cerebral amyloid induces aberrant axonal sprouting and ectopic terminal formation in amyloid precursor protein transgenic mice

AL Phinney, T Deller, M Stalder… - Journal of …, 1999 - Soc Neuroscience
A characteristic feature of Alzheimer's disease (AD) is the formation of amyloid plaques in
the brain. Although this hallmark pathology has been well described, the biological effects of …

[图书][B] Characterization of Agrin's interactions with the extracellular matrix: implications for a role in the developing and mature central nervous system, and in …

SL Cotman - 1999 - search.proquest.com
Agrin is an extracellular matrix heparan sulfate proteoglycan (HSPG) important in
synaptogenesis at the neuromuscular junction. Agrin is also abundant in the central nervous …