CD8+ T cells protect against infection from intracellular bacteria and parasites by lysing
infected targets. Here, a novel mechanism is discussed in which CD8+ cytolytic T cells …

Immunization with a plasmid DNA containing the gene encoding the catalytic domain of
trans-sialidase (TS) elicits protective immune responses against experimental Trypanosoma …

Helminth infections are frequently massive, chronic and strong inductors of Th2‐type
cytokines. This implies that infection by such parasites could alter the susceptibility to …

Trypanosoma cruzi is an obligate intracellular parasite that chronically infects mammals.
Extracellular mammalian stage trypomastigotes simultaneously express and release …

The gene family encoding a trypomastigote-specific protein restricted to the part of the
flagellum in contact with the cell body of the trypomastigote form of Trypanosoma cruzi has …

Drug treatment of late-stage human African Trypanosomiasis (HAT) in which the central
nervous system (CNS) is involved may be complicated by a severe post-treatment reactive …

The 65-kDa heat-shock protein (HSP65) is thought to play a role in host defense against
infections with various microbial pathogens and in autoimmune inflammatory disorders. We …

Trypanosoma cruzi was transformed with the Plasmodium yoelii gene encoding the circum-
sporozoite (CS) protein, which contains the well-characterized CD8+ T cell epitope …

Highly susceptible C3HeB/FeJ mice survive an otherwise lethal infection with a Brazil strain
of Trypanosoma cruzi when held at an elevated environmental temperature of 36 C. The …

The effect of sub-lethal doses of coronaviruses on the course of disease in CBA mice
experimentally infected with a mildly pathogenic strain of Trypanosoma cruzi was …