Induction of apoptosis in U937 human leukemia cells by suberoylanilide hydroxamic acid (SAHA) proceeds through pathways that are regulated by Bcl-2/Bcl-XL, c …
JA Vrana, RH Decker, CR Johnson, Z Wang, WD Jarvis… - Oncogene, 1999 - nature.com
Determinants of differentiation and apoptosis in myelomonocytic leukemia cells (U937)
exposed to the novel hybrid polar compound SAHA (suberoylanilide hydroxamic acid) have …
exposed to the novel hybrid polar compound SAHA (suberoylanilide hydroxamic acid) have …
[HTML][HTML] Non-transcriptional action of oestradiol and progestin triggers DNA synthesis
G Castoria, MV Barone, M Di Domenico… - The EMBO …, 1999 - embopress.org
The recent findings that oestradiol and progestins activate the Src/Ras/Erk s signalling
pathway raise the question of the role of this stimulation. Microinjection experiments of …
pathway raise the question of the role of this stimulation. Microinjection experiments of …
Retinoic acid selectively activates the ERK2 but not JNK/SAPK or p38 MAP kinases when inducing myeloid differentiation
A Yen, MS Roberson, S Varvayanis - In Vitro Cellular & Developmental …, 1999 - Springer
Among the three major mitogen-activated protein kinase (MAPK) cascades—the
extracellular signal regulated kinase (ERK) pathway, the c-JUN N-terminal/stress-activated …
extracellular signal regulated kinase (ERK) pathway, the c-JUN N-terminal/stress-activated …
Synthesis, Structure− Activity Relationships, and RARγ− Ligand Interactions of Nitrogen Heteroarotinoids
A Dhar, S Liu, J Klucik, KD Berlin… - Journal of medicinal …, 1999 - ACS Publications
Three heteroarotinoids containing a nitrogen atom in the first ring and a C− O linking group
between the two aryl rings were synthesized and evaluated for RAR and RXR retinoid …
between the two aryl rings were synthesized and evaluated for RAR and RXR retinoid …
Role of mitogen-activated protein kinase/extracellular signal-regulated kinase cascade in gonadotropin-releasing hormone-induced growth inhibition of a human …
A Kimura, M Ohmichi, H Kurachi, H Ikegami… - Cancer Research, 1999 - AACR
Although gonadotropin-releasing hormone agonists (GnRHa) have been used in the
therapy of the endocrine-dependent cancers, their biological mechanism remained obscure …
therapy of the endocrine-dependent cancers, their biological mechanism remained obscure …
Involvement of nuclear steroid/thyroid/retinoid receptors and of protein kinases in the regulation of growth and of c‐erbB and retinoic acid receptor expression in MCF …
SM Schneider, M Offterdinger, H Huber… - Breast cancer research …, 1999 - Springer
Nuclear steroid/thyroid/retinoid receptors and c‐erbB membrane receptor tyrosine kinases
control epithelial growth and differentiation. Retinoid receptors can dimerize with the vitamin …
control epithelial growth and differentiation. Retinoid receptors can dimerize with the vitamin …
Retinoic acid increases tyrosine phosphorylation of focal adhesion kinase and paxillin in MCF-7 human breast cancer cells
WY Zhu, CS Jones, S Amin, K Matsukuma, M Haque… - Cancer research, 1999 - AACR
Abstract Treatment of estrogen receptor (ER)-positive MCF-7 human breast cancer cells with
retinoic acid (RA) inhibited cell growth and increased cell adhesion to fibronectin. In …
retinoic acid (RA) inhibited cell growth and increased cell adhesion to fibronectin. In …
Tetradecanoyl phorbol acetate-induced microtubule reorganization is required for sustained mitogen-activated protein kinase activation and morphological …
Abstract Investigation of 12-tetradecanoyl phorbol 13-acetate (TPA)-resistant U937 cell
clones has demonstrated that the normal sustained p42 mitogen-activated protein kinase …
clones has demonstrated that the normal sustained p42 mitogen-activated protein kinase …