Introduction: Sulfonylureas have been associated with a high incidence of cardiovascular
death in diabetic patients treated with these drugs. Although the evidence on the …

The Na+/Ca2+ exchanger plays a prominent role in regulating intracellular Ca2+ levels in
cardiac myocytes and can serve as both a Ca2+ influx and efflux pathway. A novel inhibitor …

Oxidative stress plays an important role in the pathogenesis of myocardial ischemia and
infarction. Antioxidants might then be beneficial in the prevention of these diseases …

Abstract Effects of melatonin on various manifestations of ischemia/reperfusion injury of the
isolated perfused rat heart were examined. Ischemia-and reperfusion-induced ventricular …

The dangers and drawbacks inherent in radioactivity-based methods along with a
demonstrated and dramatic increase in sensitivity have precipitated a major shift towards …

The acute administration of acetaminophen to isolated, perfused guinea pig hearts appears
to have cardioprotective effects against the injury/mechanical dysfunction caused by global …

The influence of the melanocortin peptide ACTH-(1-24)(adrenocorticotropin) on the
consequences of short-term coronary ischemia (5 min) followed by reperfusion, and the …

NCX 4016, a nitro-ester of aspirin endowed with antithrombotic activity, appears to have
clinical potential in treating cardiac complications related to coronary insufficiency. This …

Rhythm disorders are common complications in diabetic patients, due to their enhanced
sensitivity to ischaemia. However, experimental studies are inconsistent, and both higher …

Intermittent exposure to the same stressor can lead to a gradual decline in physiological,
neuroendocrine and behavioral stress responses (habituation). We investigated possible …