The initial discovery of cardiac preconditioning has evolved into an exciting series of
practical surgical applications. An enormous amount of evidence demonstrating both the …

ISCHEMIC PRECONDITIONING: CLINICAL OBSERVATIONS AND APPLICATIONS
Coronary artery disease. Strategies to exploit the endogenous protective nature of ischemic …

Methods Seventeen consecutive patients with stable angina caused by a significant stenosis
of the left anterior descending (LAD) artery, who admitted into Ishinkai Yao General Hospital …

OBJECTIVES This study examined the roles of myocardial perfusion and adenosine in warm-
up angina. BACKGROUND In warm-up angina, neither the role of an adenosine-mediated …

Pravastatin has been shown, in an experimental model of ischemia reperfusion, to increase
adenosine levels, which exert a potent and protective effect on the heart. The purpose of this …

Background Ischemic preconditioning is characterized by the limitation of infarct size or
ischemic signs after one or more brief episodes of ischemia, a process that probably …

The mechanisms of ischemic cell death and reperfusion injury in the myocardium and the
ways to limit these have been under extensive research for decades. The discovery of the …

By the year 2020, it is predicted that acute coronary occlusion will be the major cause of
death in the world. Recent advances in reperfusion therapy have substantially improved …

ABSTRACT Background and Objectives: Recent reports suggest that brief periods of low-
flow ischemia (lf Isc) and reperfusion (R) before prolonged Isc mimic ischemic …

The presence of adenosine receptors on cardiovascular tissues has previously been
established on the basis of functional responses to adenosine and adenosine analogs …