The aging process is characterized by a decline in cellular functions of diverse systems of
the body, including the neuroendocrine–immune network. One neuroendocrinological …

The aim of this study was to evaluate the peripheral representation, in vitro expansion,
cytokine production, and cytotoxicity of γδ T lymphocytes from 104 healthy subjects ranging …

In the present paper, we investigated whether the phenotype, the antigen-presenting
capacity, and the migration of antigen-presenting cells (APCs), are affected by the aging …

Thymic atrophy or thymus absence causes depressed thyroid–thymus axis (TTA) efficiency
in old, young propyl-thiouracil (PTU)(experimental hypothyroidism) and in young-adult …

We evaluated the kinetics of transgene expression and humoral and cellular immune
responses against viral antigens and the product of the reporter gene LacZ in young (4 …

Melatonin (MEL) is the main neuro‐hormone of the pineal gland. The main physiological
function of MEL is to modulate variations of the light‐dark cycle and seasonal periodicity on …

Thymic involution has been envisaged as an irreversible decline that accounts for the major
manifestations of immunosenescence. However, more recent studies have demonstrated …

Metallothioneins (MTs) play pivotal roles in metal-related cell homeostasis because of their
high affinity for metals and their ability to form clusters. The main functional role of MTs is to …

Amaç: Pineal bezden salgılanan melatoninin, immün fonksiyonlar için temel bir eser
element olan çinko seviyelerini düzenlediği ileri sürülmektedir. Pinealektomize farelerde …