The role of IFN-γ in immune responses to viral infections of the central nervous system
DA Chesler, CS Reiss - Cytokine & growth factor reviews, 2002 - Elsevier
Interferon (IFN)-γ, is not only a marker of TH1 CD4, CD8 and natural killer (NK) cells, it is
also a critical antiviral mediator which is central to the elimination of viruses from the CNS. In …
also a critical antiviral mediator which is central to the elimination of viruses from the CNS. In …
TH1/TH2 cytokines in the central nervous system
D Sredni-Kenigsbuch - International Journal of Neuroscience, 2002 - Taylor & Francis
For the past 20 years it has become increasingly evident that cytokines play an important
role in both the normal development of the brain, acting as neurotrophic factors, and in brain …
role in both the normal development of the brain, acting as neurotrophic factors, and in brain …
Anticytokine therapy–new approach to the treatment of autoimmune and cytokine-disturbance diseases
SV Skurkovich, B Skurkovich, JA Kelly - Medical Hypotheses, 2002 - Elsevier
We pioneered the theory (Nature, 1974) that hyperproduced interferons (cytokines) can
bring autoimmune diseases (AD) and neutralizing these cytokines can be therapeutic. In …
bring autoimmune diseases (AD) and neutralizing these cytokines can be therapeutic. In …
Interferon‐γ acutely induces calcium influx in human microglia
S Franciosi, HB Choi, SU Kim… - Journal of …, 2002 - Wiley Online Library
The acute actions of the cytokine, interferon‐γ (IFN‐γ), on intracellular calcium [Ca2+] i
levels in human microglia were investigated. In the presence of a calcium‐containing …
levels in human microglia were investigated. In the presence of a calcium‐containing …
Selective inhibition of COX-2 is beneficial to mice infected intranasally with VSV
N Chen, A Restivo, CS Reiss - Prostaglandins & other lipid mediators, 2002 - Elsevier
Cyclooxygenase (COX) is the key enzyme for prostaglandin (PG) synthesis. PGs are
mediators of many critical physiological and inflammatory responses. There are two …
mediators of many critical physiological and inflammatory responses. There are two …
[图书][B] Prostaglandins and leukotrienes are important innate immune mediators in vesicular stomatitis virus encephalitis
N Chen - 2002 - search.proquest.com
Abstract Prostaglandins (PGs) and leukotrienes (LTs) are important pro-inflammatory
mediators. They are both derived from arachidonic acid (AA). Cyclooxygenase (COX), the …
mediators. They are both derived from arachidonic acid (AA). Cyclooxygenase (COX), the …