The roles of FLT3 in hematopoiesis and leukemia

DG Gilliland, JD Griffin - Blood, The Journal of the American …, 2002 - ashpublications.org
FLT3 is a receptor tyrosine kinase expressed by immature hematopoietic cells and is
important for the normal development of stem cells and the immune system. The ligand for …

Cultivation of hematopoietic stem and progenitor cells: biochemical engineering aspects

T Noll, N Jelinek, S Schmidt, M Biselli… - Tools and Applications of …, 2002 - Springer
The ex vivo expansion of hematopoietic cells is one of the most challenging fields in cell
culture. This is a rapidly growing area of tissue engineering with many potential applications …

CD123bright plasmacytoid predendritic cells: progenitors undergoing cell fate conversion?

MR Comeau, A Van der Vuurst de Vries… - The Journal of …, 2002 - journals.aai.org
CD123 bright plasmacytoid cells (PC) and CD1c+ peripheral blood myeloid dendritic cells
(DC) are two human DC precursors that can be expanded in vivo by Fms-like tyrosine …

Serum Flt3 ligand variation as a predictive indicator of hematopoietic stem cell mobilization

JH Haidar, A Bazarbachi, R Mahfouz… - … of Hematotherapy & …, 2002 - liebertpub.com
Flt3 ligand (FL) is a good indicator of bone marrow (BM) cellularity, having a reciprocal
relationship with white blood cell (WBC) count in aplastic anemia and chemotherapy …