Abstract Glutamate carboxypeptidase II (GCPII, EC 3.4. 17.21) is a membrane peptidase
expressed in a number of tissues such as kidney, prostate and brain. The brain form of …

Prostate specific membrane antigen (PSMA), also known as folate hydrolase (FOLH1), is a
100 kDa glycoprotein with elevated expression in prostate epithelial tissue. Expression of …

Abstract Glutamate carboxypeptidase II (GCPII, EC 3.14. 17.21) is a membrane‐bound
enzyme found on the extracellular face ofglia. The gene for this enzyme is designated …

The expression of prostate-specific membrane antigen (PSMA) and prostate-specific antigen
(PSA), two well characterized marker proteins, remains highly active in the hormone …

Prostate cancer remains the most common cancer type in men in the United States. Efforts
are increasing to evaluate and to discover diagnostic and therapeutic markers for prostate …

Glutamate carboxypeptidase II (GCPII, NAALADase, or NAAG peptidase) is a catalytic zinc
metallopeptidase. Its extracellular domain hydrolyzes the abundant neuropeptide, N-acetyl-l …

Phosphonate and phosphinate analogues of N-acylated γ-glutamylglutamate were tested for
the ability to inhibit glutamate carboxypeptidase II (GCP II). All of the compounds inhibit GCP …

Статья посвящена роли простатического специфического мембранного антигена
(ПСМА) в ранней диагностике рака простаты. Несмотря на постоянно расширяющуюся …

Uptake of methotrexate into the LNCaP human prostate cancer cells was linear for the first
60~ min. The initial rate of methotrexate uptake was highest at extracellular pH 4.5 and …

Prostate cancer (PCA) is the most common cancer and the second leading cause of death
among American men. The high mortality is greatly attributed to the lack of early detection …