Tuberculosis (TB) remains one of the main causes of morbidity worldwide, and the
emergence of multi-drug resistant (MDR) Mycobacterium tuberculosis strains in some parts …

Gatifloxacin (GAT) and moxifloxacin (MXF) were evaluated in vitro to determine their
activities against Mycobacterium tuberculosis. GAT was subsequently compared in a dose …

Multidrug-resistant tuberculosis (TB), strains resistant to at least isoniazid and rifampin, 66
make the global TB problem even more serious. Multidrug-resistant TB is difficult to treat; …

With Streptococcus pneumoniae, moxifloxacin was 4-and 10-fold more effective than
levofloxacin at restricting selection of resistant mutants and at killing resistant mutants …

We studied the activities of clarithromycin and fluoroquinolones (gatifloxacin, sitafloxacin,
levofloxacin) in combination with other antimycobacterial drugs against extracellular and …

Objectives: Studies were undertaken in order to assess the anti-Mycobacterium tuberculosis
(MTB) activities of newly developed fluoroquinolones in combination with other …

Gatiffoxacin is a recently marketed quinolone with an enhanced activity against gram-
positive bacteria compared with that of ciproffoxacin (4, 12, 13, 18). The structural …

The invention is based on the discovery that, for many drugs (eg, antiviral or antimicrobial
drugs such as antifungal or antibacterial drugs, including bacteriocidal or bacterioStatic …

With Streptococcus pneumoniae, moxifloxacin was 4-and 10-fold more effective than
levofloxacin at restricting selection of resistant mutants and at killing resistant mutants …