Lactic acid bacteria (LAB), widely used in the food industry, are present in the intestine of
most animals, including humans. The potential use of these bacteria as live vehicles for the …

Spores of the genus Bacillus have been used for a long time as probiotics for oral
bacteriotherapy both in humans and in animals. Spores are also employed in a veterinary …

This review highlights the current lack of therapeutic and prophylactic treatments for use
against inhaled biological toxins, especially those considered as potential biological warfare …

Recently, the first use of bacterial spores as vaccine vehicles was reported, showing that
mice orally immunised with Bacillus subtilis spores expressing a tetanus antigen could be …

Bordetella pertussis and Bordetella bronchiseptica are respiratory pathogens of humans
and animals respectively. Unlike many bacteria, they are able to efficiently colonise healthy …

The ability to express antigens from respiratory pathogens and induce immune responses
during oral colonization suggests that S. gordonii may be developed into a live vector for …

Vaccinations against various antigens of the central nervous system (CNS) are gaining
increasing interest as a therapeutic approach in a variety of neurological diseases such as …

The development of effective strategies for the delivery of vaccine antigens to the mucosal
tissues has received considerable attention over the past decade (reviewed in Michalek et …