Early detection represents one of the most promising approaches to reducing the growing
cancer burden. It already has a key role in the management of cervical and breast cancer …

BACKGROUND Although narrative reviews have concluded that there is strong support for
familial clustering of prostate carcinoma, the association has never systematically been …

Background: Screening for prostate cancer advances the time of diagnosis (lead time) and
detects cancers that would not have been diagnosed in the absence of screening …

Abstract Each January, the American Cancer Society (ACS) publishes a summary of existing
recommendations for early cancer detection, including updates, and/or emerging issues that …

ContextSerum prostate-specific antigen (PSA) testing is frequently used in early detection
programs for prostate cancer. While PSA testing has resulted in an increase in prostate …

Cancer ranks second only to heart disease as a leading cause of death in the United States,
making it a tremendous burden in years of life lost, patient suffering, and economic costs …

BACKGROUND Prostate cancer mortality rates in the United States declined sharply after
1991 in white men and declined after 1992 in black men. The current study was conducted …

A consensus workshop on screening [10], specifically the elements of screening RCTs, held
in March 1994 in Antwerp, Belgium, contributed in a major way to establishing the basic …

Background: The rate of death from prostate cancer has recently declined in many areas of
the world. Over the past 15 years prostate-specific antigen (PSA) screening has increased in …

The extent of effective prostate‐specific antigen (PSA) contamination in the Rotterdam
section of the ongoing European Randomized Study of Screening for Prostate Cancer …