Specific γhydroxybutyratebinding sites but loss of pharmacological effects of γhydroxybutyrate in GABAB(1)deficient mice
K Kaupmann, JF Cryan, P Wellendorph… - European Journal of …, 2003 - Wiley Online Library
Abstract γHydroxybutyrate (GHB), a metabolite of γaminobutyric acid (GABA), is proposed
to function as a neurotransmitter or neuromodulator. γHydroxybutyrate and its prodrug, γ …
to function as a neurotransmitter or neuromodulator. γHydroxybutyrate and its prodrug, γ …
Baclofen antagonizes nicotine, cocaine, and morphineinduced dopamine release in the nucleus accumbens of rat
Evidence recently provided has suggested a specific involvement of the GABAergic system
in modulating positive reinforcing properties of several drugs of abuse through an action on …
in modulating positive reinforcing properties of several drugs of abuse through an action on …
Changes in GABAA receptor gene expression associated with selective alterations in receptor function and pharmacology after ethanol withdrawal
E Sanna, MC Mostallino, F Busonero… - Journal of …, 2003 - Soc Neuroscience
Changes in the expression of subunits of the GABA type A (GABAA) receptor are implicated
in the development of ethanol tolerance and dependence as well as in the central …
in the development of ethanol tolerance and dependence as well as in the central …
GABA systems, benzodiazepines, and substance dependence
RJ Malcolm - Journal of Clinical Psychiatry, 2003 - psychiatrist.com
Alterations in the γ-aminobutyric acid (GABA) receptor complex and GABA
neurotransmission influence the reinforcing and intoxicating effects of alcohol and …
neurotransmission influence the reinforcing and intoxicating effects of alcohol and …
Baclofen for maintenance treatment of opioid dependence: a randomized double-blind placebo-controlled clinical trial [ISRCTN32121581]
SM Assadi, R Radgoodarzi, SA Ahmadi-Abhari - BMC psychiatry, 2003 - Springer
Background Results of preclinical studies suggest that the GABA B receptor agonist
baclofen may be useful in treatment of opioid dependence. This study was aimed at …
baclofen may be useful in treatment of opioid dependence. This study was aimed at …
Suppression of alcohol delirium tremens by baclofen administration: a case report
Delirium tremens (DT) is a clinical condition that appears in some patients affected by
severe alcohol withdrawal syndrome (AWS). DT represents a serious complication, being …
severe alcohol withdrawal syndrome (AWS). DT represents a serious complication, being …
Pharmacologic treatments manage alcohol withdrawal, relapse prevention
R Malcolm - Psychiatric Annals, 2003 - journals.healio.com
edication management is the central focus of treating alcohol withdrawal and has
increasingly become a greater part of the therapy of relapse prevention. Several other …
increasingly become a greater part of the therapy of relapse prevention. Several other …
Baclofen: Alcohol Withdrawal
J Generali, DJ Cada - Hospital Pharmacy, 2003 - journals.sagepub.com
Off-Label Drug Uses This Hospital Pharmacy feature is extracted from Off-Label DrugFacts,
a quarterly publication available from Facts and Comparisons. Off-Label DrugFacts is a …
a quarterly publication available from Facts and Comparisons. Off-Label DrugFacts is a …
[PDF][PDF] Valproic Acid
V Acid - 2003 - psychrights.org
Case 3: 09-cv-00080-TMB Document 78-21 Filed 03/24/2010 Page 1 of 142 or less with a
therapeutic serum range of 50 to 100 mcg/mL)(Prod Info DEPAKENE (R) oral capsule 2006; …
therapeutic serum range of 50 to 100 mcg/mL)(Prod Info DEPAKENE (R) oral capsule 2006; …