New insights into the roles of agrin
G Bezakova, MA Ruegg - Nature Reviews Molecular Cell Biology, 2003 - nature.com
The heparan sulphate proteoglycan agrin is expressed as several isoforms in various
tissues. Agrin is best known as a crucial organizer of postsynaptic differentiation at the …
tissues. Agrin is best known as a crucial organizer of postsynaptic differentiation at the …
Heparan sulphate proteoglycans in Alzheimer's disease and amyloid‐related disorders
J Van Horssen, P Wesseling… - The Lancet …, 2003 - thelancet.com
Proteoglycans are associated with all kinds of amyloid deposits in the human body. These
complex macromolecules, in particular heparan sulphate proteoglycans, have also been …
complex macromolecules, in particular heparan sulphate proteoglycans, have also been …
Synaptic plasticity and cell cycle activation in neurons are alternative effector pathways: the 'Dr. Jekyll and Mr. Hyde concept'of Alzheimer's disease or the yin and yang …
T Arendt - Progress in neurobiology, 2003 - Elsevier
Mental actions are based on the dynamic organization of neuronal networks. In particular,
phylogenetically young brain areas (eg, cortical associative circuits) involved in the …
phylogenetically young brain areas (eg, cortical associative circuits) involved in the …
Structural alterations at the neuromuscular junctions of matrix metalloproteinase 3 null mutant mice
M VanSaun, AA Herrera, MJ Werle - Journal of neurocytology, 2003 - Springer
Matrix metalloproteinases are important regulators of extracellular matrix molecules and cell-
cell signaling. Antibodies to matrix metalloproteinase 3 (MMP3) recognize molecules at the …
cell signaling. Antibodies to matrix metalloproteinase 3 (MMP3) recognize molecules at the …
Proteoglycans and amyloidogenic proteins in peripheral amyloidosis
F Gervais, C Morissette, X Kong - Current Medicinal Chemistry …, 2003 - ingentaconnect.com
Amyloidogenic proteins have the characteristic of adopting a β-sheet conformation and
assembling into fibrils. Although similar in fibrillar appearance, each type of peripheral …
assembling into fibrils. Although similar in fibrillar appearance, each type of peripheral …
Overexpression of full-length but not N-terminal truncated isoform of microtubule-associated protein (MAP) 1B accelerates apoptosis of cultured cortical neurons
Y Uchida - Journal of Biological Chemistry, 2003 - ASBMB
β-amyloid (Aβ) is presumed to play a pathogenic role in Alzheimer's disease (AD). However,
there is an imperfect correlation between Aβ deposition and neuronal loss or dementia. To …
there is an imperfect correlation between Aβ deposition and neuronal loss or dementia. To …
Reduced expression of the cystic fibrosis transmembrane conductance regulator gene in the hypothalamus of patients with Alzheimer's disease
SA Lahousse, EG Stopa, AE Mulberg… - Journal of …, 2003 - content.iospress.com
Background: The cystic fibrosis transmembrane conductance regulator (CFTR) gene
encodes a~ 150–165 kD glycoprotein that is mutated in individuals with cystic fibrosis …
encodes a~ 150–165 kD glycoprotein that is mutated in individuals with cystic fibrosis …
Vascular dementia: A diagnostic conundrum for the clinical neuropsychologist
R Paul, K Garrett, R Cohen - Applied Neuropsychology, 2003 - Taylor & Francis
The contribution of cerebrovascular disease (CVD) to cognitive impairment in older persons
is an important determination rendered by clinical neuropsychologists. However, it is often …
is an important determination rendered by clinical neuropsychologists. However, it is often …
[图书][B] Agrin in the CNS: Mapping the functional domains of agrin required for signaling through a receptor localized at neuronal synapses
CL Hoover - 2003 - search.proquest.com
The formation and maintenance of chemical synapses is essential for the function of the
central nervous system (CNS). Investigations of these processes at the neuromuscular …
central nervous system (CNS). Investigations of these processes at the neuromuscular …