Na+, K+-ATPase: the new face of an old player in pathogenesis and apoptotic/hybrid cell death

SP Yu - Biochemical pharmacology, 2003 - Elsevier
The Na+, K+-ATPase is a ubiquitous membrane transport protein in mammalian cells,
responsible for establishing and maintaining high K+ and low Na+ in the cytoplasm required …

Ouabain-and marinobufagenin-induced proliferation of human umbilical vein smooth muscle cells and a rat vascular smooth muscle cell line, A7r5

J Abramowitz, C Dai, KK Hirschi, RI Dmitrieva… - Circulation, 2003 - Am Heart Assoc
Background—We studied the growth-promoting effects of 2 sodium pump–selective
cardiotonic steroids, ouabain and marinobufagenin, on cultured cells from vascular smooth …

Inhibition of Na+, K+-ATPase by ouabain triggers epithelial cell death independently of inversion of the [Na+] i/[K+] i ratio

D Pchejetski, S Taurin, S Der Sarkissian… - Biochemical and …, 2003 - Elsevier
Treatment with ouabain led to massive death of principal cells from collecting ducts (C7-
MDCK), indicated by cell swelling, loss of mitochondrial function, an irregular pattern of DNA …

Na/K pump and intracellular monovalent cations: novel mechanism of excitation–transcription coupling involved in inhibition of apoptosis

S Taurin, P Hamet, SN Orlov - Molecular Biology, 2003 - Springer
The Na/K pump plays a key role in the regulation of the intracellular concentrations of
monovalent cations and related cell function leading to electrogenesis and excitation …

Na/K-НАСОС И ВНУТРИКЛЕТОЧНЫЕ МОНОВАЛЕНТНЫЕ КАТИОНЫ: НОВЫЙ МЕХАНИЗМ СОПРЯЖЕНИЯ ВОЗБУЖДЕНИЯ С ТРАНСКРИПЦИЕЙ …

С Тора, П Хамет, СН Орлов - Молекулярная биология, 2003 - elibrary.ru
Na/K-Hacoc играет ключевую роль в регуляции внутриклеточной концентрации
моновалентных катионов и в родственных функциях клетки, приводящих к …

Na+− H+ exchanger as a target for intervention in cardiovascular remodelling

SN Orlov - Journal of Hypertension, 2003 - journals.lww.com
During the last two decades, several laboratories have reported that enhanced permeability
for Naþ, initially discovered as an enhanced rate of isotope transmembrane exchange in …

[引用][C] 哇巴因与高血压心血管重塑

任延平, 吕卓人 - 中华高血压杂志, 2003