Mathematical programs with equilibrium constraints (MPECs) form a relatively new and
interesting subclass of nonlinear programming problems. In this paper we propose a novel …

Optimal design under unknown information is a key task in process systems engineering.
This study considers formulations that incorporate two types of unknown input parameters …

This paper offers a brief overview of past work as well as a comprehensive summary of our
efforts based on the operability framework introduced by Vinson and Georgakis (in: C …

A new approach is presented to the optimization based design of continuous processes in
the presence of parametric uncertainty. In contrast to previous works focusing on process …

The synthesis and optimization of plant-wide waste management policies under uncertainty
is the subject of this paper. The combinatorial synthesis methodology (Chakraborty, A.; …

A large number of publications available on determining the feasible region and the
operability limits for a design are all limited due to the assumption that the feasible space is …

Flexibility analysis is of prime importance in chemical process systems, since it permits the
creation of chemical processes, which can satisfy all design specifications in spite of …

This paper presents the incorporation of process flexibility into a methanol synthesis loop
operating under catalyst deactivation. A design methodology is discussed with regard to …

A new approach is presented to the optimization based design of continuous processes in
the presence of parametric uncertainty. In contrast to pre® ious works focusing on process …

Detailed mathematical models are increasingly being used by companies to gain
competitive advantage through such applications as model-based process design, control …