We previously showed that resveratrol (3, 4′, 5-trihydroxystilbene) stimulates NO
production and is cardioprotective in rat heart subjected to ischemia–reperfusion (I/R rat …

The cardiotonic and antidysrhythmic effects of four triterpenoid derivatives, namely oleanolic
acid (OA), ursolic acid (UA), and uvaol (UV), isolated from the leaves of African wild olive …

Objectives: Brief episodes of myocardial ischemia-reperfusion employed during reperfusion
after a prolonged ischemic insult may attenuate the total ischemia-reperfusion injury. This …

Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), the (n-3) PUFA found in
fish oils, exert antiarrhythmic effects during ischemia. Flaxseed is the richest plant source of …

Background—Heart failure often complicates myocardial infarction (MI), and sarcoplasmic/
endoplasmic reticulum Ca2+-ATPase (SERCA2a) is underexpressed in the failing …

We examined cardioprotective effect of chronic hypoxia and the time course of its recovery
under normoxic conditions. Adult male Wistar rats were exposed to intermittent hypobaric …

In Germany, hydroalcoholic extracts from hawthorn (Crataegus spp.) leaves with flowers are
approved drugs for the treatment of mild forms of heart insufficiency. Besides cardiotonic …

Exercise provides protection against ischemia–reperfusion (IR)-induced arrhythmias,
myocardial stunning, and infarction. An exercise-induced increase in myocardial …

Depression is an important public health problem and is considered to be an independent
risk factor for coronary artery disease. The pathophysiological mechanisms that link …

Despite decades of research, there are few effective ways to treat ventricular fibrillation (VF),
ventricular tachycardia (VT), or cardiac ischemia that show a significant survival benefit. Our …