Mast cells are not only necessary for allergic reactions, but recent findings indicate that they
are also involved in a variety of neuroinflammatory diseases, especially those worsened by …

OBJECTIVE: To review the increasing amount of data that support or dispel the use of
dietary supplements in the treatment of inflammatory conditions that involve mast cells, such …

Background Evidence from a genetic linkage study had suggested a possible syndrome in
some families with panic disorder (PD). This syndrome includes bladder problems (possibly …

Problem: Mast cells are critical in allergic and inflammatory diseases such as interstitial
cystitis, which is often clinically associated with or mistaken as endometriosis. Mast cells had …

PURPOSE: In this ongoing review we characterize interstitial cystitis in men, identifying
multiple clinical factors in the diagnosis and treatment of men with interstitial cystitis …

Mast cells (MCs) initiate immune responses from mucosal surfaces and perivascular spaces.
Stem cell factor (SCF) regulates MC development and viability, but the role of innate serum …

Evidence from clinical trials and experience derived from managing patients with asthma
justify a broader role for leukotriene (LT) blockers in asthma management than that …

Background Interstitial cystitis (IC) is a chronic bladder disorder of unknown etiology.
Antiproliferative factor (APF), a peptide found in the urine of IC patients, has previously been …

Bacterial infections of the urinary bladder are very common, and the role of mast cells in
these infections is invariably thought of as a detrimental one. However, recent studies have …

PURPOSE: Most recently attention has turned to the secretory properties of smooth muscle
cells. Monocyte chemoattractant protein-1 (MCP-1) is a potent chemokine that causes mast …