Accurate staging of non–small-cell lung cancer (NSCLC) determines prognosis and
facilitates decisions regarding treatment options. Unfortunately, even after an apparently …

The diagnosis of hepatocellular carcinoma (HCC) includes detection of the index lesion,
staging of the lesion within the liver, and assessment for extrahepatic metastasis. HCC is a …

OBJECTIVE: To develop a reliable technique to enrich for rare cells in blood suspensions
using only negative selection steps including a flow-through immunomagnetic cell …

Purpose: The presence of tumor cells in bone marrow has been reported to represent an
important prognostic indicator in breast cancer, but the clinical significance of circulating …

Abstract Purpose: Cytokeratins (CKs) have been recognized for> 20 years as structural
marker proteins specific for epithelial cells. Recent expression profiling analyses indicate …

Purpose: The aim of the study was to explore the value of analyzing bone marrow (BM) for
the presence of isolated tumor cell (s)(ITCs) in disease-free breast cancer patients 3 years …

Background The prescence of circulating tumor cells (CTCs) in the peripheral blood of
cancer patients and their frequency has been correlated with disease status. Methods In this …

Purpose: EMMPRIN (extracellular matrix metalloprotease inducer) is a glycosylated member
of the immunoglobulin superfamily known to stimulate the production of matrix …

The mechanisms of long-term survival of occult breast cancer cells in the bone marrow
microenvironment are not known. Using selected bone marrow stromal components with …

Purpose: The detection of disseminated occult breast cancer cells in peripheral blood and
bone marrow is associated with poor prognosis. Since a high proportion of these cells …