Are multiple markers the future of prostate cancer diagnostics?

SD Mikolajczyk, Y Song, JR Wong, RS Matson… - Clinical …, 2004 - Elsevier
Prostate specific antigen (PSA) is the most successful and widely employed cancer serum
marker in use today. There is growing evidence that the introduction of wide PSA screening …

Update on screening for prostate cancer with prostate-specific antigen

HP Schmid, W Riesen, L Prikler - Critical reviews in oncology/hematology, 2004 - Elsevier
Serum prostate-specific antigen (PSA) determination in conjunction with digital rectal
examination (DRE) is recommended by the majority of clinical guidelines for early detection …

Results of a randomized, population‐based study of biennial screening using serum prostate‐specific antigen measurement to detect prostate carcinoma

J Hugosson, G Aus, H Lilja, P Lodding… - … International Journal of …, 2004 - Wiley Online Library
BACKGROUND The purpose of the current study was to evaluate the effectiveness of a
prostate carcinoma screening program in which serum prostate‐specific antigen (PSA) …

Lead time associated with screening for prostate cancer

M Törnblom, H Eriksson, S FRANZen… - … journal of cancer, 2004 - Wiley Online Library
Screening serum levels of prostate‐specific antigen (PSA) is now a major strategy for early
detection of prostate cancer (PC). Quantification of the lead time thus obtained is important …

Characteristics of prostate cancers detected at low PSA levels

W Horninger, AP Berger, H Rogatsch… - The …, 2004 - Wiley Online Library
BACKGROUND When age-referenced PSA levels as recommended by Oesterling et al. 1
were used as a biopsy criterion, only 25% of the cancers detected in a population based …

Early detection of prostate cancer in African-American men through use of multiple biomarkers: human kallikrein 2 (hK2), prostate-specific antigen (PSA), and free PSA …

BJ Martin, JA Finlay, K Sterling, M Ward… - Prostate Cancer and …, 2004 - nature.com
Recent studies have reported enhanced prostate cancer detection in Caucasians with
serum human glandular kallikrein 2 (hK2) in combination with total-(tPSA) and free-prostate …

Screening for prostate cancer: current recommendations

SS Wilson, ED Crawford - Urologic Clinics, 2004 - urologic.theclinics.com
An estimated 220,900 new cases of prostate cancer were diagnosed in the United States in
2003, and 28,900 men died of the disease during that year [1]. A global effort to decrease …

Prostate-specific antigen and screening for prostate cancer

M Han, PH Gann, WJ Catalona - Medical Clinics, 2004 - medical.theclinics.com
In 1970, Ablin et al [1, 2] reported on the existence of tissue-specific antigens in the normal
and pathologic prostate gland. In 1979, Wang et al [3] identified prostatic antigen, later …

The use of modeling to understand the impact of screening on US mortality: examples from mammography and PSA testing

EJ Feuer, R Etzioni, KA Cronin… - Statistical Methods in …, 2004 - journals.sagepub.com
Surveillance data represent a vital resource for understanding the impact of cancer control
interventions on the population cancer burden. However, population cancer trends are a …

Controversies in prostate cancer screening

AM Murphy, JM McKIERNAN, CA Olsson - The Journal of urology, 2004 - Elsevier
PURPOSE:: Prostate cancer is the most common cancer in men and the second most
common cause of cancer death in men, and yet controversy continues to surround the …