A mechanistic understanding of aging has yet to be described; this paper puts forth a new
theory that has the potential to explain aging in all sexually reproductive life forms. The …

Male hypogonadism is characterized by abnormally low serum testosterone levels
associated with typical symptoms, including mood disturbance, sexual dysfunction …

Type 2 diabetes is associated with lower total testosterone (T) levels in cross-sectional
studies. However, it is not known whether the defect is primary or secondary. We …

Older men, particularly those with low serum testosterone (T) levels, might benefit from T
therapy to improve bone mineral density (BMD) and reduce fracture risk. Concerns exist …

To examine the relationship of total and free testosterone and sex hormone-binding globulin
(SHBG) with central obesity in men, we studied 1548 men aged 25–84 years that took part in …

Introduction Endocrine disorders of sex steroid hormones may adversely affect men's sexual
function. Aim To provide expert opinions/recommendations concerning state‐of‐the‐art …

As men age, serum testosterone levels decrease, a factor that may contribute to some
aspects of age-related physiological deterioration. Although androgen replacement has …

During illness, major changes in thyroid hormone metabolism and regulation occur; these
are collectively known as non-thyroidal illness and are characterized by decreased serum …

Western populations represent an ageing society with continuing gains being made in life
expectancy; a male born in Australia has a healthy life expectancy of 70 years with slightly …

There has been dramatic worldwide increase in the elderly population during the 20th
Century. The number of Americans aged 65 years and older climbed to 35 million in 2000 …