Structure and function of amyloid in Alzheimer's disease
C Morgan, M Colombres, MT Nuñez… - Progress in …, 2004 - Elsevier
This review is focused on the structure and function of Alzheimer's amyloid deposits.
Amyloid formation is a process in which normal well-folded cellular proteins undergo a self …
Amyloid formation is a process in which normal well-folded cellular proteins undergo a self …
Polyanions and the proteome
LTS Jones, B Yazzie, CR Middaugh - Molecular & Cellular Proteomics, 2004 - ASBMB
The behavior of the proteome reflects spatial and temporal organization both within and
without cells. We propose that various macromolecular entities possessing polyanionic …
without cells. We propose that various macromolecular entities possessing polyanionic …
Glypican‐1 as an Aβ binding HSPG in the human brain: Its localization in DIG domains and possible roles in the pathogenesis of Alzheimer's disease
N Watanabe, W Araki, DH Chui, T Makifuchi… - The FASEB …, 2004 - Wiley Online Library
Previous studies have suggested that heparan sulfate proteoglycans (HSPGs) play a role in
deposition of β‐amyloid protein (Aβ) in the Alzheimer's disease (AD) brain. In the present …
deposition of β‐amyloid protein (Aβ) in the Alzheimer's disease (AD) brain. In the present …
AGRIN 在老年鼠大脑皮质和海马的表达
刘丙方， 王唯析， 高尔静， 徐群渊 - 中国组织化学与细胞化学杂志, 2004 - cqvip.com
目的观察蛋白聚糖-agrin 在大鼠大脑皮质和海马的表达, 探讨agrin 与记忆的关系.
方法用抗agrin 的多克隆抗体, 免疫组化方法检测成年大鼠, 记忆正常老年鼠以及记忆障碍的老年 …
方法用抗agrin 的多克隆抗体, 免疫组化方法检测成年大鼠, 记忆正常老年鼠以及记忆障碍的老年 …
Inhibition of ß-Amyloid Peptide-Induced Microglial Cell Activation by Glycosaminoglycans
C Morissette, F Gervais, P Tremblay - Amyloid and Amyloidosis, 2004 - taylorfrancis.com
Glycosaminoglycans (GAGs) have been shown to contribute to the development of amyloid
diseases. In Alzheimer's disease (AD), senile plaques, which are mostly composed of the ß …
diseases. In Alzheimer's disease (AD), senile plaques, which are mostly composed of the ß …